METHYLANDROSTANOLONE
17A-methylandrostan-17B-ol-3-one--dea*schedule ii
CAS: 521-11-9
Molecular Formula: C20H32O2
METHYLANDROSTANOLONE - Names and Identifiers
| Name | 17A-methylandrostan-17B-ol-3-one--dea*schedule ii |
| Synonyms | MESTALINE Mestanlone MESTANOLONE mestanolone METHYLANDROSTANOLONE METHYLDIHYDROTESTOSTERONE 17ALPHA-METHYLDIHYDROTESTOSTERONE 3-KETO-17B-HYDROXY-17A-METHYL-5A-ANDROSTANE 5ALPHA-ANDROSTANE-17ALPHA-METHYL-17BETA-OL-3-ONE 17A-methylandrostan-17B-ol-3-one--dea*schedule ii 5-ALPHA-ANDROSTAN-17-ALPHA-METHYL-17-BETA-OL-3-ONE (5alpha,17beta)-17-hydroxy-17-methylandrostan-3-one 1,5-Alpha-Andresten-17-Alpha-Methyl-17-Beta-OL-3-One 17-beta-hydroxy-17-alpha-methyl-5-alpha-androstan-3-one (5S,14S,17R)-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one |
| CAS | 521-11-9 |
| EINECS | 208-302-6 |
| InChI | InChI=1/C20H32O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h13,15-17,22H,4-12H2,1-3H3/t13-,15?,16?,17-,18?,19?,20+/m0/s1 |
| InChIKey | WYZDXEKUWRCKOB-YDSAWKJFSA-N |
METHYLANDROSTANOLONE - Physico-chemical Properties
| Molecular Formula | C20H32O2 |
| Molar Mass | 304.47 |
| Density | 1.0279 (rough estimate) |
| Melting Point | 191 °C |
| Boling Point | 385.28°C (rough estimate) |
| Flash Point | 177.6°C |
| Vapor Presure | 1.16E-08mmHg at 25°C |
| Appearance | neat |
| Merck | 5915 |
| pKa | 15.15±0.60(Predicted) |
| Storage Condition | Controlled Substance, -20°C Freezer |
| Refractive Index | 1.4824 (estimate) |
| Physical and Chemical Properties | Crystallization (ethyl acetate). Melting point 224-226 °c. Soluble in acetone, ethanol, ethyl ether, ethyl acetate, insoluble in water. |
| Use | For the treatment of male hypogonadism and sperm reduction infertility |
METHYLANDROSTANOLONE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 40 - Limited evidence of a carcinogenic effect |
| Safety Description | S22 - Do not breathe dust. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | BV8064500 |
| HS Code | 29372900 |
METHYLANDROSTANOLONE - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| introduction | mestonolone (mestonolone) alias mestonolone, mestonolone, is used to treat male hypogonadism and sperm reduction Infertility. With the development of society, the demand for meixionosaurus (US testosterone) is increasing. At present, the production process of meixionosaurus (US testosterone) is complex, and the purity of the products produced is low, resulting in high product prices. |
| Pharmacological effects | Testosterone is an orally effective anabolic hormone. Assimilation is similar to methyltestosterone, but androgen activity is only 1/4. US testosterone is characterized by small androgen effect and strong protein assimilation. It can promote protein synthesis, inhibit protein heterogenesis, maintain positive nitrogen balance, promote appetite, increase muscle, and increase weight. Promote the deposition of calcium and phosphorus in tissues, promote the formation of osteocyte stroma, accelerate calcification and bone growth. Promote tissue regeneration and granulation formation, accelerate wound and ulcer repair. Lower cholesterol and improve lipid metabolism. Clinically, it is mainly used for negative nitrogen balance caused by chronic wasting diseases, osteoporosis, severe infections and burns to promote the growth of premature infants and immature infants. It can be used for long-term non-union fractures, hypercholesterolemia, postpartum and post-illness weakness. |
| application | mexonolone (mexonolone) is an important intermediate for the production of steroid hormone drugs. Using it as a raw material, it can produce a variety of common androgen drugs such as Kangfulong and Kanglilong. |
| precautions | 1. liver disease, kidney disease, hypertension, prostate cancer or hypertrophy, pregnant women do not use. Avoid light and keep it airtight. 2. In order to improve the curative effect, appropriate amount of protein, sugar and vitamins should be taken at the same time. |
| Use | It is an intermediate for male hypogonadism and sperm reduction infertility, dehydromethyltestosterone. for the treatment of male hypogonadism and infertile spermatozoa |
| Production method | It is prepared by chromic acid oxidation with 17 α-methyl -3,17 β-androstane diol. |
Last Update：2024-04-09 21:50:46
