METHYLCARBAMOYLCHLORIDE
Methylcarbamoylchloride
CAS: 6452-47-7
Molecular Formula: C2H4ClNO
METHYLCARBAMOYLCHLORIDE - Names and Identifiers
| Name | Methylcarbamoylchloride |
| Synonyms | Methylcarbamic chloride N-Methylchloroformamide methylcarbamic chloride Methylcarbamoylchloride METHYLCARBAMOYLCHLORIDE METHYLAMINOFORMYL CHLORIDE N-Methylcarbamoyl chloride Methylaminoformyl chloride N-(Chloroformyl)methylamine Methylcarbamic acid chloride n-methylaminoformyl chloride |
| CAS | 6452-47-7 |
| EINECS | 229-253-7 |
| InChI | InChI=1/C2H4ClNO/c1-4-2(3)5/h1H3,(H,4,5) |
METHYLCARBAMOYLCHLORIDE - Physico-chemical Properties
| Molecular Formula | C2H4ClNO |
| Molar Mass | 93.51 |
| Density | 1.185±0.06 g/cm3(Predicted) |
| Melting Point | 45°C |
| Boling Point | 93°C (dec.) |
| Solubility | Acetonitrile, Chloroform (Slightly), DMSO |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 10.67±0.46(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Stability | Air Sensitive, Hygroscopic, Moisture Sensitive, Volatile |
| Refractive Index | 1.415 |
| Physical and Chemical Properties | Pure methylcarbamoyl chloride as white crystals, M.P. 45 ℃ (decomposition), soluble in benzene and other organic solvents, alkali and water decomposition, easy to cause explosion, unstable at high temperature, the eyes, respiratory tract irritation. |
METHYLCARBAMOYLCHLORIDE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
METHYLCARBAMOYLCHLORIDE - Reference Information
| Use | methylcarbamoyl chloride can be widely used as carbamate insecticides such as SEC-dinoyl, carbofuran, isoprocarb, methomyl, intermediates of methacryl and methacryl, etc. pesticides-intermediates of carbamate insecticides and herbicides. |
| production method | is obtained by reacting methylamine with phosgene. The 40% methylamine aqueous solution was vaporized, dried and mixed with phosgene at a ratio of 1:1.3 (by volume), methylamine at 4 m3/h, phosgene enters the preheater for preheating respectively at a rate of 8.6/h (content: 60%-70%), the preheating temperature of methylamine is controlled at 220-260 ℃, and the phosgene is controlled at 200-240 ℃. The two preheated gases enter the test tube and are synthesized at 280-300 ° C. To obtain the gas carbamoyl chloride. Carbon tetrachloride (or chlorobenzene solution) is then recycled at 0-20 °c to obtain about 10% carbamoyl chloride (or chlorobenzene) solution, or cooled below 35-40 °c to a liquid product. methylcarbamoyl chloride is prepared by the reaction of methylamine with phosgene. Reaction equation: 40% methylamine aqueous solution was vaporized by CH3NH2 + COCl2 → CH3NHCOCl, and after drying, the ratio (volume) of phosgene and methylamine was 1: 1.3, phosgene at 8.6/h (content 60% ~ 70%) Into the preheater preheating, methyl amine preheating temperature control in 220~260 ℃, phosgene control in 220~240 ℃. The two preheated gases enter the Venturi and are synthesized at 280-300 °c to give methyl carbamoyl chloride. Then with carbon tetrachloride (or chlorobenzene solution) in 0~20 deg C cycle absorption, get about 10% of carbamoyl chloride carbon tetrachloride (or chlorobenzene) solution, alternatively, it can be cooled to a liquid product below 35-40 °c. |
Last Update：2024-04-10 22:29:15
