ML167
ML167
CAS: 1285702-20-6
Molecular Formula: C19H17N3O3
ML167 - Names and Identifiers
ML167 - Physico-chemical Properties
| Molecular Formula | C19H17N3O3 |
| Molar Mass | 335.36 |
| Solubility | DMSO: ≥ 125 mg/mL |
| Appearance | powder |
| Color | off-white to gray to brown |
| Storage Condition | -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| In vitro study | In Caco-2 experiments, ML167 was used as a probe for Clk4 with high cell permeability. |
ML167 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | 46 - If swallowed, seek medical advice immediately and show this container or label. |
| WGK Germany | 3 |
ML167 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.982 ml | 14.91 ml | 29.819 ml |
| 5 mM | 0.596 ml | 2.982 ml | 5.964 ml |
| 10 mM | 0.298 ml | 1.491 ml | 2.982 ml |
| 5 mM | 0.06 ml | 0.298 ml | 0.596 ml |
Last Update：2024-01-02 23:10:35
ML167 - Reference Information
| biological activity | ML167 (CID 44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, and its selectivity is 10 times higher than similar kinase Clk1-3 and Dyrk1A/1B. |
| target | TargetValue CLK4 136 nM CLK1 1522 nM CLK2 1648 nM Dyrk1B 4420 nM |
| Target | Value |
| CLK4 | 136 nM |
| CLK1 | 1522 nM |
| CLK2 | 1648 nM |
| Dyrk1B | 4420 nM |
| in vitro study | in Caco-2 experiments, ML167, as a probe for Clk4, has high cell permeability. |
Last Update：2024-04-09 21:54:55
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Product Name: ML167 Visit Supplier Webpage Request for quotationCAS: 1285702-20-6
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Spot supply
Product Name: ML167 Visit Supplier Webpage Request for quotationCAS: 1285702-20-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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