Methyl-4-amino-3-fluorobenzoate

Methyl-4-amino-3-fluorobenzoate - Names and Identifiers

Name	Methyl-4-amino-3-fluorobenzoate
Synonyms	Methyl-4-amino-3-fluorobenzoate Methyl 3-fluoro-4-aMinobenzoate 2-Fluoro-4-(methoxycarbonyl)aniline 3-Fluoro-4-aminobenzoic acid methyl ester Benzoic acid, 4-aMino-3-fluoro-, Methyl ester
CAS	185629-32-7

Methyl-4-amino-3-fluorobenzoate - Physico-chemical Properties

Molecular Formula	C8H8FNO2
Molar Mass	169.15
Density	1.264
Melting Point	109-110°C
Boling Point	296℃
Flash Point	133℃
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive	Irritant
MDL	MFCD08689703
Use	Methyl 4-amino-3-fluorobenzene carboxylate is a carboxylate derivative, which can be used as a pharmaceutical intermediate.

Methyl-4-amino-3-fluorobenzoate - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Hazard Class	IRRITANT

Methyl-4-amino-3-fluorobenzoate - Upstream Downstream Industry

Raw Materials

4-AMINO-3-FLUOROBENZOIC ACID
3-Methoxy-4-nitrobenzoic acid
3-Fluoro-4-nitrobenzoic acid
METHYL 3,4-DIFLUOROBENZOATE
METHYL 3-FLUORO-4-NITROBENZENECARBOXYLATE
Methanol

Methyl-4-amino-3-fluorobenzoate - Introduction

Methyl-4-amino-3-fluorobenzoate, the chemical formula is C8H8FNO2, is an organic compound. The following is information about the properties, use, preparation and safety of the compound:

Nature:
-Appearance: Methyl-4-amino-3-fluorobenzoate is usually a white crystalline solid.
-Solubility: It is soluble in non-polar solvents such as ether and dichloromethane, but insoluble in water.
-Melting point: The melting point of this compound is about 62-65°C.

Use:
-Advanced organic synthesis reagents: Methyl-4-amino-3-fluorobenzoate are often used as reagents or intermediates in organic synthesis reactions.
-Drug development: It can be used as raw materials and intermediates for synthetic drugs in the pharmaceutical industry.

Preparation Method:
The preparation of Methyl-4-amino-3-fluorobenzoate is usually carried out by the following steps:
1. Take methyl 3-fluorobenzoate as the starting material.
2. reacting methyl 3-fluorobenzoate with ammonia under alkaline conditions to form methyl 4-amino-3-fluorobenzoate.

Safety Information:
-The specific acute toxicity of the compound has not been determined, so appropriate protective measures should be taken when using it, including wearing chemical protective gloves and glasses.
-Avoid inhalation, ingestion or contact with skin and avoid prolonged contact.
-should be in a well ventilated place to operate, avoid inhalation of its vapor.
-The compound should be sealed during storage and kept away from fire and oxidizing agents.

Please note that the use and handling of this compound should follow relevant safety guidelines and laboratory practices.

Last Update：2024-04-09 20:49:11