Methyl-PEG9-amine

Name	2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine
Synonyms	MPEG9-NH2 m-PEG9-amine Methyl-PEG9-amine 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
CAS	211859-73-3

Molecular Formula	C19H41NO9
Molar Mass	427.53
Density	1.060
Boling Point	484.3±40.0 °C(Predicted)
pKa	8.74±0.10(Predicted)
Storage Condition	2-8℃
In vitro study	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

biological activity	m-PEG9-Amine is a PROTAC connection bridge and belongs to PEG class. m-PEG9-Amine can be used to synthesize a series of PROTAC molecules. m-PEG9-Amine is a degradable (cleavable) ADC connection bridge for the synthesis of antibody drug conjugates (ADCs).
target	Cleavable PEGs
in vitro study	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Last Update：2024-04-09 21:11:58