| Name | Midinyanglin |
| Synonyms | MDYL N-23 Midinyanglin |
| Molecular Formula | C10H17Q4N2PS |
| Physical and Chemical Properties | The pure chemical product is a colorless oily liquid, and the industrial product is light yellow. Relative density 1.1977 (1.2029) (20 ℃), refractive index n20D1.5096. The solubility in water is 375mg/L (15 ℃), and it is easily soluble in various organic solvents such as ethyl acetate, ethanol, acetone, toluene, acetonitrile, ether, benzene, dichloroethane, etc. It will decompose when heated or when exposed to acid or alkali. |
| Use | Uses of organic phosphorus insecticides, with stomach poison and contact killing effect, has the characteristics of internal absorption, effective on stinging and suction of insect pests, has special effects on rice gall midge. For the prevention and control of rice Chilo suppressalis, triplex, Rice planthopper, Rice bract, Rice thrips, leaf hopper, longitudinal leaf roller Borer, cotton bollworm, red bollworm, Red Spider, cotton aphid, can also be used to control cotton bollworm eggs and ground tiger and other underground pests. Such as the control of the above pests in rice field, with 50% cream per hectare 2.2~4.5L, spray on water; Control land Tiger, with 50% cream 3L/hm2, water 30 ~ 45kg, spraying 300kg of fine soil. This product is sensitive to sorghum and should not be used. |
cyanamide aqueous solution method
Preparation of Methylisourea Hydrolyzes lime nitrogen, the reaction temperature is controlled at 40~45 ℃, the residue is filtered, and the filtrate is treated with cation exchange resin for calcium ions. In the presence of HCl, it reacts with methanol to obtain methylisourea hydrochloride.
Preparation of methoxymethyl hydroxypyrimidine Methyl isourea salt and ethyl acetoacetate react in sodium hydroxide solution to prepare methoxymethyl hydroxypyrimidine.
Synthesis of pyrimidophane, O,O-diethylthiophosphoryl chloride reacts with methoxymethyl hydroxyl pyrimidine salt to produce pyrimidophane. It can also be prepared by reacting O,O-diethylthiophosphoryl chloride with methoxymethyl hydroxypyrimidine in the presence of an acid binding agent. It has also been reported in the literature that in the presence of nucleophile 4-N,N-dimethylaminopyridine (DMAP), anhydrous sodium charcoal as acid binding agent and ethyl acetate as solvent, O,O-diethylthiophosphoryl chloride is reacted with 2-methoxy-4-methyl-6-hydroxypyrimidine for 3~4h at room temperature or reflux temperature, with a yield of 99%.
Dimethyl sulfate method
The dimethyl sulfate is heated and reacted with urea to generate O-methylisourea bismethyl sulfate salt, and then reacted with ethyl acetoacetate in an alkaline aqueous solution to generate 2-methoxy-4-methyl-6-hydroxypyrimidine, The product refluxes with diethoxy thiophosphoric chloride in the presence of anhydrous sodium carbonate in ethyl acetate to obtain pyrimidinoxyphosphorus.