Name | Morusin |
Synonyms | Moracin Morusin Mulberrochromene morusin 62596-29-6 Morusin(Mulberrochromene) |
CAS | 62596-29-6 |
EINECS | 300-006-7 |
Molecular Formula | C25H24O6 |
Molar Mass | 420.45 |
Density | 1.303 |
Melting Point | 232-235℃ |
Boling Point | 656.7±55.0 °C(Predicted) |
Solubility | Soluble in DMSO, hot methanol, insoluble in petroleum ether and chloroform. |
Appearance | Pale yellow powder |
pKa | 6.55±0.60(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
MDL | MFCD09953814 |
Physical and Chemical Properties | Soluble in DMSO, hot methanol, insoluble in petroleum ether and chloroform. Derived from Morous alba L. Root bark of yellow-brown coarse bark removed |
Overview | It is reported that the root bark of Morus L. Mainly contains flavonoids, coumarins, aromatic benzofuran derivatives, polysaccharides and other ingredients, of which the flavonoids of sangxinsu (also known as morusin, morusin) with anti-tumor, antibacterial, analgesic, anti-HIV activity [2]. Studies have shown that. Sangxinsu has anti-tumor and anti-HIV activity, mainly exists in the yellow-brown skin of cortex Mori, which indicates that the outer skin of cortex Mori contains a variety of active ingredients. |
chromatographic conditions | chromatographic conditions Alhima C18 column (4.6 × 250lllm,5mm); Mobile phase acetonitrile. Water (58:42); Detection wavelength 270nlll; Column greenhouse temperature; Flow rate L 0 m L-rain ~. Under these conditions, sangxinsu and other components can achieve baseline separation (see figure 1). FIG. 1 chromatogram of brucine reference substance A; Medicinal Herb B; 1. Sangxinsu |
pharmacological effects | studies have shown. Sangxinsu has anti-tumor and anti-HIV activity [2]. |
Use | Anti-tumor, antibacterial, analgesic, anti-HIV. Only for scientific research experiments, not for diagnosis and treatment. FIG. 2 Use of sangxinsu for content determination/identification/pharmacological experiment, etc. Pharmacological effects: anti-tumor, antibacterial, analgesic, anti-HIV activity. |
source of ingredients | This product is the main phenolic components in mulberry root bark. The content of sangxinsu in cortex Mori was related to the growth period and the thickness of root bark. The content of sangxinsu in two-year-old cortex Mori from the same variety and the same origin is higher than that in five-year-old cortex Mori; The content of sangxinsu in the sample with thin skin is higher. The content of Mulberry in the root bark of the same plant is lower than that of the root bark [2]. |
reference material | [1] sangxinsu. A hundred-chain database. [Citation date: 2017.08.20] [2] Zhen Yu-ying, Ye Zhao-Bo, Dong Ting-Xia, etc. Determination of the content of sangxinsu in cortex Mori [J]. Chinese Journal of Traditional Chinese Medicine, 2007,32(11):1038-1040.DOI:10.3321/j.issn:1001-5302.2007.11.010. [3] Morusin. Pubchem.ncbi.nlm.nih.gov. [Reference date: 2017.08.20] |