N(alpha)-boc-N(delta)-trityl-L-glutamine - Names and Identifiers
Name | N(alpha)-boc-N(delta)-trityl-L-glutamine
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Synonyms | BOC-GLN(TRT)-OH Boc-Gln(Trt)-OH BOC-L-TRITYL GLUTAMINE BOC-L-GLUTAMINE(TRITYL) N-Boc-N'-trityl-L-glutamine Nα-Boc-Nδ-trityl-L-glutamine BOC-N-DELTA-TRITYL-L-GLUTAMINE N-ALPHA-BOC-N-DELTA-TRITYL-L-GLUTAMINE N-ALPHA-T-BOC-GAMMA-TRITYL-L-GLUTAMINE N(alpha)-boc-N(delta)-trityl-L-glutamine N-ALPHA-T-BUTOXYCARBONYL-N-GAMMA-TRITYL-L-GLUTAMINE Benzoic acid, 2-[[[(1R)-4-amino-1-carboxy-4-oxobutyl]amino]diphenylmethyl]-, 1-(1,1-dimethylethyl) ester
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CAS | 132388-69-3
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InChI | InChI=1/C29H32N2O5/c1-28(2,3)36-27(35)22-16-10-11-17-23(22)29(20-12-6-4-7-13-20,21-14-8-5-9-15-21)31-24(26(33)34)18-19-25(30)32/h4-17,24,31H,18-19H2,1-3H3,(H2,30,32)(H,33,34)/t24-/m1/s1 |
N(alpha)-boc-N(delta)-trityl-L-glutamine - Physico-chemical Properties
Molecular Formula | C29H32N2O5
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Molar Mass | 488.57 |
Density | 1.199g/cm3 |
Boling Point | 696.8°C at 760 mmHg |
Flash Point | 375.2°C |
Vapor Presure | 2.2E-20mmHg at 25°C |
Appearance | White powder |
BRN | 4340082 |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.587 |
MDL | MFCD00153305 |
N(alpha)-boc-N(delta)-trityl-L-glutamine - Risk and Safety
WGK Germany | 3 |
HS Code | 29242990 |
N(alpha)-boc-N(delta)-trityl-L-glutamine - Introduction
N-Boc-N '-trityl-L-glutamine (N-Boc-N'-trityl-L-glutamine, abbreviated as Boc-Gln(Trt)-OH) is an organic compound. It has the following properties:
1. Appearance: white crystalline powder.
2. molecular formula: C39H35N3O6
3. Molecular weight: 641.71g/mol
4. Melting point: 148-151°C
5. Solubility: Soluble in most organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane.
6. Stability: relatively stable under conventional experimental conditions.
In chemical synthesis, N-Boc-N '-trityl-L-glutamine is often used as an amino acid protecting group or intermediate. Its main uses include:
1. used as glutamine protecting group in peptide and protein synthesis.
2. In the research of synthetic drugs, it is used to synthesize glutamine analogs.
3. used as an intermediate to synthesize other organic compounds.
The method for preparing N-Boc-N '-trityl-L-glutamine is generally as follows:
1. First, react N-protected glutamine (such as N-Boc-L-glutamine) with trityl halide (such as trityl chloride) to obtain N-Boc-N '-trityl-L-glutamine.
Safety Information:
N-Boc-N '-trityl-L-glutamine, as an organic compound, is relatively safe under correct use and storage. However, the following matters still need to be noted:
1. Avoid contact with eyes, skin and respiratory tract. Use chemical protective gloves and goggles.
2. Store in a dry, cool place.
3. Comply with safety procedures and properly handle and dispose of the waste of the compound.
Last Update:2024-04-09 21:01:54