N(alpha)-boc-N(gamma)-trityl-L-aspara-gine
N(alpha)-boc-N(gamma)-trityl-L-aspara-gine
CAS: 132388-68-2
Molecular Formula: C28H30N2O5
N(alpha)-boc-N(gamma)-trityl-L-aspara-gine - Names and Identifiers
| Name | N(alpha)-boc-N(gamma)-trityl-L-aspara-gine |
| Synonyms | Boc-Asn(Trt)-OH BOC-ASN(TRT)-OH BOC-L-ASPARAGINE(TRITYL) N-Boc-N'-trityl-L-asparagine Boc-N-beta-Trityl-L-Asparagine N-ALPHA-T-BOC-N-BETA-TRITYL-ASPARAGINE N-ALPHA-T-BOC-BETA-TRITYL-L-ASPARAGINE N(alpha)-boc-N(gamma)-trityl-L-aspara-gine Nα-tert-Butoxycarbonyl-Nγ-trityl-L-asparagine N-ALPHA-T-BUTOXYCARBONYL-N-BETA-TRITYL-L-ASPARAGINE NALPHA-TERT-BUTOXYCARBONYL-NGAMMA-TRITYL-L-ASPARAGINE |
| CAS | 132388-68-2 |
| EINECS | 2017-001-1 |
| InChI | InChI=1/C28H30N2O5/c1-27(2,3)35-26(34)29-23(25(32)33)19-24(31)30-28(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-18,23H,19H2,1-3H3,(H,29,34)(H,30,31)(H,32,33)/t23-/m0/s1 |
N(alpha)-boc-N(gamma)-trityl-L-aspara-gine - Physico-chemical Properties
| Molecular Formula | C28H30N2O5 |
| Molar Mass | 474.55 |
| Density | 1.202g/cm3 |
| Melting Point | ~205°C (dec.) |
| Boling Point | 711°C at 760 mmHg |
| Flash Point | 383.8°C |
| Vapor Presure | 3.22E-21mmHg at 25°C |
| Appearance | White powder |
| Color | White to Almost white |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.582 |
| MDL | MFCD00153299 |
N(alpha)-boc-N(gamma)-trityl-L-aspara-gine - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 2924 29 70 |
| Hazard Class | IRRITANT |
N(alpha)-boc-N(gamma)-trityl-L-aspara-gine - Introduction
NAA-tert-butoxycarbonyl N Γ-trityl aspartamide is an organic compound, commonly referred to by the abbreviation Boc-Phe-OtBu. It has the formula C30H37NO4 and is a white solid.
Nature:
Boc-Phe-OtBu is hydrophobic and hardly soluble in water, but easily soluble in organic solvents such as methanol, ethanol and dichloromethane. It is relatively stable to light and heat.
Use:
Boc-Phe-OtBu are mainly used for protecting groups and reaction intermediates in organic synthesis. In the synthesis, it can be used to protect aromatic amino acids, in the synthesis of polypeptides and proteins, protecting the active groups to prevent the occurrence of side reactions. In addition, it can also be used to prepare other compounds, such as drugs, dyes and organic materials.
Preparation Method:
The preparation of Boc-Phe-OtBu is mainly accomplished by chemical reaction. One common method is to react p-benzoic acid with t-butyl hydroxyformate to produce p-tert-butoxycarbonyl benzoate. It is then reacted with triphenylamine to give the final product Boc-Phe-OtBu.
Safety Information:
The Boc-Phe-OtBu is relatively safe under normal use. However, as a chemical, it still needs to be stored and handled properly. Avoid contact with strong oxidants, prevent inhalation of dust and avoid skin contact. During use, wear appropriate personal protective equipment, such as gloves and protective glasses. In the event of accidental contact or ingestion, seek medical advice immediately and provide information to the doctor about the chemical. Local safety rules and regulations should be followed when handling and disposing of waste.
Nature:
Boc-Phe-OtBu is hydrophobic and hardly soluble in water, but easily soluble in organic solvents such as methanol, ethanol and dichloromethane. It is relatively stable to light and heat.
Use:
Boc-Phe-OtBu are mainly used for protecting groups and reaction intermediates in organic synthesis. In the synthesis, it can be used to protect aromatic amino acids, in the synthesis of polypeptides and proteins, protecting the active groups to prevent the occurrence of side reactions. In addition, it can also be used to prepare other compounds, such as drugs, dyes and organic materials.
Preparation Method:
The preparation of Boc-Phe-OtBu is mainly accomplished by chemical reaction. One common method is to react p-benzoic acid with t-butyl hydroxyformate to produce p-tert-butoxycarbonyl benzoate. It is then reacted with triphenylamine to give the final product Boc-Phe-OtBu.
Safety Information:
The Boc-Phe-OtBu is relatively safe under normal use. However, as a chemical, it still needs to be stored and handled properly. Avoid contact with strong oxidants, prevent inhalation of dust and avoid skin contact. During use, wear appropriate personal protective equipment, such as gloves and protective glasses. In the event of accidental contact or ingestion, seek medical advice immediately and provide information to the doctor about the chemical. Local safety rules and regulations should be followed when handling and disposing of waste.
Last Update：2024-04-09 20:45:29
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Product Name: Boc-Asn(Trt)-OH Visit Supplier Webpage Request for quotationCAS: 132388-68-2
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