N(alpha)-fmoc-L-tyrosine
N(alpha)-fmoc-L-tyrosine
CAS: 92954-90-0
Molecular Formula: C24H21NO5
N(alpha)-fmoc-L-tyrosine - Names and Identifiers
| Name | N(alpha)-fmoc-L-tyrosine |
| Synonyms | FMOC-TYR-OH Fmoc-Tyr-OH Fmoc-L-Tyr-OH FMOC-TYROSINE Fmoc-L-Tyrsine Fmoc-L-tyrosine N-FMOC-L-TYROSINE Nalpha-Fmoc-L-Tyrosine Nalpha-Fmoc-L-tyrosine N-ALPHA-FMOC-L-TYROSINE N(alpha)-fmoc-L-tyrosine N-[(9H-fluoren-9-ylmethoxy)carbonyl]tyrosine N-[9H-Fluoren-9-ylmethoxy)carbonyl]-L-tyrosine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-TYROSINE N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-TYROSINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-TYROSINE (S)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-(4-HYDROXY-PHENYL)-PROPIONIC ACID |
| CAS | 92954-90-0 |
| InChI | InChI=1/C24H21NO5/c26-16-11-9-15(10-12-16)13-22(23(27)28)25-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22,26H,13-14H2,(H,25,29)(H,27,28)/t22-/m0/s1 |
N(alpha)-fmoc-L-tyrosine - Physico-chemical Properties
| Molecular Formula | C24H21NO5 |
| Molar Mass | 403.43 |
| Density | 1.336±0.06 g/cm3(Predicted) |
| Melting Point | 182-187°C |
| Boling Point | 672.6±55.0 °C(Predicted) |
| Specific Rotation(α) | -22 º (c=1%, DMF) |
| Flash Point | 360.6°C |
| Vapor Presure | 5.24E-19mmHg at 25°C |
| Appearance | White powder |
| BRN | 3573123 |
| pKa | 2.95±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | -22.0 ° (C=1, DMF) |
| MDL | MFCD00134890 |
N(alpha)-fmoc-L-tyrosine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S27 - Take off immediately all contaminated clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 2924 29 70 |
N(alpha)-fmoc-L-tyrosine - Introduction
N(alpha)-fmoc-L-tyrosine, also known as N(alpha)-fmoc-L-tyrosine, is a derivative of the naturally occurring amino acid tyrosine. The following is a brief description of its nature, use, preparation and safety information:
Nature:
N(alpha)-fmoc-L-tyrosine is a white to off-white solid with high solubility in organic solvents such as dimethyl sulfoxide (DMSO), tetrahydrofuran (THF) and methanol. Its chemical structure has an N(alpha)-fmoc protecting group and a tyrosine side chain.
Use:
N(alpha)-fmoc-L-tyrosine are widely used in chemical biology and organic synthesis. It is often used as a protected amino acid in peptide synthesis to prevent unwanted side reactions by protecting the phenolic group on the hydroxyl group. In addition, N(alpha)-fmoc-L-tyrosine can be used to synthesize biologically active peptides, proteins, and drug molecules.
Method:
N(alpha)-fmoc-L-tyrosine are typically obtained by chemical synthesis. Specifically, N(alpha)-fmoc-L-tyrosine can be produced by reacting L-tyrosine with N(alpha)-fmoc-amino acid. The reaction can be carried out in an organic solvent and under specific reaction conditions, such as dimethyl sulfoxide catalyzed by an organic base.
Safety Information:
When used correctly, N(alpha)-fmoc-L-tyrosine is relatively safe. However, as a chemical reagent, it still requires proper handling and storage. Contact with eyes, skin and administration should be avoided as it may cause irritation and discomfort. Appropriate personal protective equipment, such as laboratory gloves and eye protection glasses, should be worn when using the compound. In addition, it should be operated in a well-ventilated environment. Before handling this compound, carefully read and follow the relevant safety instructions.
Nature:
N(alpha)-fmoc-L-tyrosine is a white to off-white solid with high solubility in organic solvents such as dimethyl sulfoxide (DMSO), tetrahydrofuran (THF) and methanol. Its chemical structure has an N(alpha)-fmoc protecting group and a tyrosine side chain.
Use:
N(alpha)-fmoc-L-tyrosine are widely used in chemical biology and organic synthesis. It is often used as a protected amino acid in peptide synthesis to prevent unwanted side reactions by protecting the phenolic group on the hydroxyl group. In addition, N(alpha)-fmoc-L-tyrosine can be used to synthesize biologically active peptides, proteins, and drug molecules.
Method:
N(alpha)-fmoc-L-tyrosine are typically obtained by chemical synthesis. Specifically, N(alpha)-fmoc-L-tyrosine can be produced by reacting L-tyrosine with N(alpha)-fmoc-amino acid. The reaction can be carried out in an organic solvent and under specific reaction conditions, such as dimethyl sulfoxide catalyzed by an organic base.
Safety Information:
When used correctly, N(alpha)-fmoc-L-tyrosine is relatively safe. However, as a chemical reagent, it still requires proper handling and storage. Contact with eyes, skin and administration should be avoided as it may cause irritation and discomfort. Appropriate personal protective equipment, such as laboratory gloves and eye protection glasses, should be worn when using the compound. In addition, it should be operated in a well-ventilated environment. Before handling this compound, carefully read and follow the relevant safety instructions.
Last Update：2024-04-09 20:45:29
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