N,N,3-三甲基氮杂啶-3-胺
N,N,3-Trimethylazetidin-3-amine
CAS: 149696-13-9
Molecular Formula: C6H14N2
N,N,3-三甲基氮杂啶-3-胺 - Names and Identifiers
| Name | N,N,3-Trimethylazetidin-3-amine |
| Synonyms | N,N,3-Trimethyl-3-azetidinamine N,N,3-Trimethylazetidin-3-amine N,N,3-trimethylazetidin-3-amine 3-Azetidinamine, N,N,3-trimethyl- |
| CAS | 149696-13-9 |
N,N,3-三甲基氮杂啶-3-胺 - Physico-chemical Properties
| Molecular Formula | C6H14N2 |
| Molar Mass | 114.19 |
| Density | 0.92±0.1 g/cm3(Predicted) |
| Boling Point | 141.1±8.0 °C(Predicted) |
| pKa | 10.42±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD17170039 |
N,N,3-三甲基氮杂啶-3-胺 - Introduction
N,N,3-Trimethylazetidin-3-amine, also known as TMAD(Trimethyl-3-adamantylammonium), is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
1. Nature:
-Appearance: TMAD is a colorless or light yellow solid powder.
-Solubility: low solubility in water, but can be dissolved in ethanol, acetone and other organic solvents.
-Melting point: about 206-210 ℃.
2. Use:
-Catalyst: TMAD is often used as an amine-based catalyst in organic synthesis for the catalytic control step of organic reactions.
-drug synthesis: It is also used in the synthesis of some important drugs, such as the synthesis of retroviral drugs of HIV virus.
3. Preparation method:
The preparation method of-TMAD can be obtained by reacting isobutyl deoxybase and phenol under appropriate reaction conditions.
4. Safety Information:
-The specific toxicity information of TMAD has not been clearly reported, but it is generally believed that it has no obvious harm to human health.
-Avoid direct contact with eyes, skin and respiratory tract.
-During use or storage, it is necessary to avoid high temperature and fire sources.
-Pay attention to good ventilation conditions during operation and avoid inhaling gas or dust.
-Observe relevant safety procedures and personal protective measures when handling. If there is any discomfort, please seek medical attention in time.
1. Nature:
-Appearance: TMAD is a colorless or light yellow solid powder.
-Solubility: low solubility in water, but can be dissolved in ethanol, acetone and other organic solvents.
-Melting point: about 206-210 ℃.
2. Use:
-Catalyst: TMAD is often used as an amine-based catalyst in organic synthesis for the catalytic control step of organic reactions.
-drug synthesis: It is also used in the synthesis of some important drugs, such as the synthesis of retroviral drugs of HIV virus.
3. Preparation method:
The preparation method of-TMAD can be obtained by reacting isobutyl deoxybase and phenol under appropriate reaction conditions.
4. Safety Information:
-The specific toxicity information of TMAD has not been clearly reported, but it is generally believed that it has no obvious harm to human health.
-Avoid direct contact with eyes, skin and respiratory tract.
-During use or storage, it is necessary to avoid high temperature and fire sources.
-Pay attention to good ventilation conditions during operation and avoid inhaling gas or dust.
-Observe relevant safety procedures and personal protective measures when handling. If there is any discomfort, please seek medical attention in time.
Last Update：2024-04-09 02:00:42
