N,N,N-trimethyl-1,1-bis(1-methylethoxy)amine

N,N,N-trimethyl-1,1-bis(1-methylethoxy)amine - Names and Identifiers

Name	N,N-dimethylformamide diisopropyl acetal
Synonyms	1,1-DIISOPROPOXYTRIMETHYLAMINE Dimethyl(diisopropoxymethyl)amine N,N-dimethylformamide dipropyl acetal N,N-Dimethylformamide dimethylacetate N,N-dimethylformamide diisopropyl acetal 1,1-diisopropoxy-n,n-dimethylmethylamine N,N-DIMETHYLFORMAMIDE DI-N-PROPYL ACETAL N,N-DIMETHYLFORMAMIDE DIISOPROPYL ACETAL N,N,N-trimethyl-1,1-bis(1-methylethoxy)amine N,N-Dimethyl-α,α-bis(isopropyloxy)methanamine N,N-dimethyl-1,1-bis(propan-2-yloxy)methanamine
CAS	18503-89-4
EINECS	242-386-5
InChI	InChI=1/C9H21NO2/c1-7(2)11-9(10(5)6)12-8(3)4/h7-9H,1-6H3

N,N,N-trimethyl-1,1-bis(1-methylethoxy)amine - Physico-chemical Properties

Molecular Formula	C9H21NO2
Molar Mass	175.27
Density	0.838 g/mL at 25 °C(lit.)
Boling Point	79-80°C60mm Hg(lit.)
Flash Point	74°F
Vapor Presure	3.41mmHg at 25°C
BRN	1901978
pKa	5.47±0.50(Predicted)
Storage Condition	RT, dry
Refractive Index	n20/D 1.409(lit.)

N,N,N-trimethyl-1,1-bis(1-methylethoxy)amine - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R10 - Flammable
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	UN 1993 3/PG 3
WGK Germany	3
Hazard Class	3.2
Packing Group	III

N,N,N-trimethyl-1,1-bis(1-methylethoxy)amine - Introduction

N,N-dimethylformamide diisopropyl acetal(N,N-Dimethylformamide Diisopropyl Acetal) is an organic compound. Its molecular formula is C9H19NO2, structural formula is (CH3)2NCH(OCH(CH3)2)2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
N,N-dimethylformamide diisopropyl acetal is a colorless to pale yellow liquid with low volatility. It is soluble in most organic solvents such as alcohols, ethers and aromatic hydrocarbons.

Use:
N,N-dimethylformamide diisopropyl acetal is mainly used as a protective reagent in organic synthesis. It can protect the aldehyde and ketone functional groups from further reaction with other reagents. In the synthesis of complex organic molecules, this protecting reagent can selectively protect specific functional groups, thereby achieving the synthesis of target compounds.

Method:
N,N-dimethylformamide diisopropyl acetal can be prepared by the following steps:
1. Condensation of dimethylformamide and isopropanol at low temperature using an acid catalyst.
2. The product is precipitated and then washed with an organic solvent.
3. Finally, the product is purified by distillation or crystal separation.

Safety Information:
N,N-dimethylformamide the toxicity of diisopropyl acetal is low, it is still necessary to pay attention to safe operation. It is a flammable liquid and should avoid high temperatures, open flames and sparks during storage and use. At the same time, care should be taken to avoid inhalation, contact with the skin and ingestion. It must be operated in a well-ventilated place and thoroughly cleaned after use. In case of any discomfort or accident, seek medical help immediately. Please read the safety data sheet (SDS) and follow the correct safe operating procedures before use.

Last Update：2024-04-10 22:29:15