N,N-BIS(BENZYLOXYCARBONYL)-1H-PYRAZOLE-1

N,N-BIS(BENZYLOXYCARBONYL)-1H-PYRAZOLE-1 - Names and Identifiers

Name	N,N'-Bis-Z-1-Guanylpyrazole
Synonyms	Pyrazol(Z)2 Pyrazole(Z)2 N,N'-Bis-Z-1-Guanylpyrazole N,N'-Di-Z-1h-Pyrazol-1-Carbamidine N,N'-Di-Z-1h-Pyrazole-1-Carbamidine N,N'-DI-Z-1H-PYRAZOLE-1-CARBAMIDINE N,N'-Di-Cbz-1H-pyrazole-1-carboxamidine N,N-BIS(BENZYLOXYCARBONYL)-1H-PYRAZOLE-1 N,N-Bis(Benzyloxycarbonyl)-1h-Pyrazole-1 N,N-Bisbenzyloxycarbonyl-1-Guanylpyrazole Pyrazol(Z)2N,N'-Di-Cbz-1H-pyrazole-1-carbaMidine dibenzyl (1H-pyrazol-1-ylmethylylidene)biscarbamate -Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine Benzyl ((((benzyloxy)carbonyl)aMino)(1H-pyrazol-1-yl)Methylene)carbaMate N,N-Bisbenzyloxycarbonyl-1-Guanylpyrazole, N,N-Di-Cbz-1h-Pyrazole-1-Carboxamidine N-[phenylmethoxycarbonylamino(1-pyrazolyl)methylidene]carbamic acid (phenylmethyl) ester
CAS	152120-55-3
InChI	InChI=1/C20H18N4O4/c25-19(27-14-16-8-3-1-4-9-16)22-18(24-13-7-12-21-24)23-20(26)28-15-17-10-5-2-6-11-17/h1-13H,14-15H2,(H,22,23,25,26)
InChIKey	NRBUVVTTYMTSKM-UHFFFAOYSA-N

N,N-BIS(BENZYLOXYCARBONYL)-1H-PYRAZOLE-1 - Physico-chemical Properties

Molecular Formula	C20H18N4O4
Molar Mass	378.39
Density	1.25±0.1 g/cm3(Predicted)
Melting Point	90-96°C
Appearance	powder to crystal
Color	White to Almost white
pKa	6.66±0.46(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.611
Physical and Chemical Properties	WGK Germany:3

N,N-BIS(BENZYLOXYCARBONYL)-1H-PYRAZOLE-1 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
FLUKA BRAND F CODES	10-21
HS Code	29331990

N,N-BIS(BENZYLOXYCARBONYL)-1H-PYRAZOLE-1 - Introduction

An N,N'-Bis-Z-1-Guanylpyrazole (abbreviated as DBU-PZ) is an organic compound. The following is a description of the nature, use, preparation and safety information of the DBU-PZ:

Nature:
- DBU-PZ is a colorless to light yellow solid.
-Its chemical formula is C16H17N3O3, and its relative molecular mass is 299.33.
- DBU-PZ is relatively stable at room temperature and soluble in common organic solvents such as ethanol, dimethylformamide, etc.

Use:
- DBU-PZ is commonly used as an alkali catalyst in organic synthesis. It is highly alkaline and can be used to catalyze various organic reactions.
-It can be used for some lone electron docking acceptor activation reactions, such as hydrogen oxidation reaction, olefin cyclization reaction, etc.
- DBU-PZ can also be used as an intermediate in the synthesis of other pyrazole compounds.

Method:
- DBU-PZ are generally prepared by reacting N,N'-bis (benzyloxycarbonyl)-LH-pyrazole with methylamidine.
-The reaction is typically carried out in dimethylformamide or dichloromethane under an inert atmosphere.
-As the reaction proceeds, the methylamidine gradually reacts with the pyrazole Group to form a DBU-PZ product.

Safety Information:
- DBU-PZ dust may be irritating to eyes, skin and respiratory tract. Care should be taken to avoid contact.
-Wear appropriate protective equipment such as chemical safety glasses and gloves when performing experiments.
-When using or storing DBU-PZ, avoid contact with oxidants and strong acids to avoid dangerous reactions.

Last Update：2024-04-10 22:29:15