N-α-Fmoc-L-aspartic acid α-tert butyl ester
Fmoc-Asp-OtBu
CAS: 129460-09-9
Molecular Formula: C23H25NO6
N-α-Fmoc-L-aspartic acid α-tert butyl ester - Names and Identifiers
| Name | Fmoc-Asp-OtBu |
| Synonyms | Fmoc-Asp-OBu Fmoc-Asp-OBut Fmoc-Asp-OtBu 1-tert-Butyl N-Fmoc-L-aspartate Fmoc-L-aspartic acid 1-tert-butyl ester L-FMOC-ASPARTIC ACID ALPHA-T-BUTYL ESTER L-Fmoc-Aspartic acid alpha-tert-butyl ester N-α-Fmoc-L-aspartic acid α-tert butyl ester L-Fmoc-Aspartic Acid Alpha-Tert-Butyl Ester N-ALPHA-L-ASPARTIC ACID ALPHA TERT-BUTYL ESTER NALPHA-9-Fluorenylmethoxycarbonyl-L-aspartic acid ALPHA-tert-butyl ester N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartic Acid 1-tert-Butyl Ester (3S)-4-tert-butoxy-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoic acid (non-preferred name) |
| CAS | 129460-09-9 |
| InChI | InChI=1/C23H25NO6/c1-23(2,3)30-21(27)19(12-20(25)26)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,25,26)/t19-/m0/s1 |
| InChIKey | VZXQYACYLGRQJU-IBGZPJMESA-N |
N-α-Fmoc-L-aspartic acid α-tert butyl ester - Physico-chemical Properties
| Molecular Formula | C23H25NO6 |
| Molar Mass | 411.45 |
| Density | 1.251±0.06 g/cm3(Predicted) |
| Melting Point | 90-98°C |
| Boling Point | 617.4±55.0 °C(Predicted) |
| Flash Point | 327.2°C |
| Vapor Presure | 4.21E-16mmHg at 25°C |
| Appearance | Powder |
| Color | White to Almost white |
| pKa | 4.08±0.19(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.576 |
| MDL | MFCD00065631 |
N-α-Fmoc-L-aspartic acid α-tert butyl ester - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | WGK 2 water endanger |
| HS Code | 29224999 |
| Hazard Class | IRRITANT |
N-α-Fmoc-L-aspartic acid α-tert butyl ester - Introduction
Fluorenylmethoxycarbonyl-aspartate-l-tert-butyl ester (Fmoc-Asp(tBu)-OH) is a commonly used protecting group for aspartic acid. The following is a description of its nature, use, formulation and safety information:
Nature:
-Chemical formula: C26H27NO6
-Molecular weight: 449.49g/mol
-Appearance: White crystalline solid
-Melting point: 205-207°C
Use:
- Fmoc-Asp(tBu)-OH is usually used in peptide synthesis in solid phase synthesis as an aspartic acid protecting group.
-It can generate peptide chains by introducing aspartic acid residues into the synthetic peptide sequence by means of solid phase synthesis.
Preparation Method:
- Fmoc-Asp(tBu)-OH can be obtained by reacting isopropyl acetate or sodium hydroxide with Fmoc-Asp(tBu)-OH.
Safety Information:
- Fmoc-Asp(tBu)-OH is widely used in industry and laboratories, and is generally considered to be a relatively safe substance.
-but still need to pay attention to its toxicity and irritation.
-When handling it, wear appropriate protective equipment, such as gloves and goggles, to prevent contact with skin or eyes.
-When storing and handling, it is recommended to keep it in a dry, cool place, away from fire and oxidizing agents.
Please note that the safety of chemicals needs to be treated with caution. Experiments should be carried out in accordance with safe operating guidelines and waste disposal in accordance with relevant regulations.
Nature:
-Chemical formula: C26H27NO6
-Molecular weight: 449.49g/mol
-Appearance: White crystalline solid
-Melting point: 205-207°C
Use:
- Fmoc-Asp(tBu)-OH is usually used in peptide synthesis in solid phase synthesis as an aspartic acid protecting group.
-It can generate peptide chains by introducing aspartic acid residues into the synthetic peptide sequence by means of solid phase synthesis.
Preparation Method:
- Fmoc-Asp(tBu)-OH can be obtained by reacting isopropyl acetate or sodium hydroxide with Fmoc-Asp(tBu)-OH.
Safety Information:
- Fmoc-Asp(tBu)-OH is widely used in industry and laboratories, and is generally considered to be a relatively safe substance.
-but still need to pay attention to its toxicity and irritation.
-When handling it, wear appropriate protective equipment, such as gloves and goggles, to prevent contact with skin or eyes.
-When storing and handling, it is recommended to keep it in a dry, cool place, away from fire and oxidizing agents.
Please note that the safety of chemicals needs to be treated with caution. Experiments should be carried out in accordance with safe operating guidelines and waste disposal in accordance with relevant regulations.
Last Update：2024-04-10 22:29:15
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Product Name: N-Fmoc-L-aspartic acid 1-tert-butyl ester Visit Supplier Webpage Request for quotationCAS: 129460-09-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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