N-((6-((Di-tert-butylphosphino)methyl)pyridin-2-yl)methyl)-N-ethylethanamine
2-(Di-t-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine
CAS: 863971-66-8
Molecular Formula: C19H35N2P
N-((6-((Di-tert-butylphosphino)methyl)pyridin-2-yl)methyl)-N-ethylethanamine - Names and Identifiers
N-((6-((Di-tert-butylphosphino)methyl)pyridin-2-yl)methyl)-N-ethylethanamine - Physico-chemical Properties
| Molecular Formula | C19H35N2P |
| Molar Mass | 322.47 |
| Density | 0.936 g/mL at 25 °C |
| Boling Point | 130 °C(Press: 0.02 Torr) |
| Flash Point | 67℃ |
| Appearance | liquid |
| Color | yellow |
| pKa | 8.65±0.25(Predicted) |
| Storage Condition | Argon filled storage |
| Sensitive | air sensitive |
| Refractive Index | n20/D1.519 |
| MDL | MFCD11656080 |
N-((6-((Di-tert-butylphosphino)methyl)pyridin-2-yl)methyl)-N-ethylethanamine - Risk and Safety
| Risk Codes | R15 - Contact with water liberates extremely flammable gases R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S43 - In case of fire use ... (there follows the type of fire-fighting equipment to be used.) |
| UN IDs | UN 3148 4.3 / PGIII |
| WGK Germany | 3 |
N-((6-((Di-tert-butylphosphino)methyl)pyridin-2-yl)methyl)-N-ethylethanamine - Introduction
2-(Di-t-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine is an organic compound with the chemical formula C18H36N2P. It is a pyridine derivative with a phosphino and a diethylaminomethyl group.
This compound has the following properties:
-Appearance: Colorless liquid or solid
-Melting point: about 60-65 ℃
-Solubility: Soluble in organic solvents such as methanol, ethanol and dichloromethane
One of the main uses of 2-(Di-t-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine is to play an important role as a ligand in organometallic catalyzed reactions. It can form complexes with transition metals and is used to catalyze the addition of carbonyl compounds and carbonyl reduction reactions.
A common method for preparing 2-(Di-t-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine is by introducing a phosphine and diethylamine group on the aminomethyl group on pyridine. This can be obtained by reacting pyridine with diethylamine and di-tert-butylphosphinecarboxaldehyde.
Regarding safety information, the 2-(Di-t-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine is generally safer under normal conditions of use. However, like most chemicals, precautions should be taken when using them. It can cause eye and skin irritation, so wear appropriate protective equipment (such as gloves, goggles and laboratory coats) and avoid inhalation or ingestion. Any work with this compound should follow proper laboratory practices.
This compound has the following properties:
-Appearance: Colorless liquid or solid
-Melting point: about 60-65 ℃
-Solubility: Soluble in organic solvents such as methanol, ethanol and dichloromethane
One of the main uses of 2-(Di-t-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine is to play an important role as a ligand in organometallic catalyzed reactions. It can form complexes with transition metals and is used to catalyze the addition of carbonyl compounds and carbonyl reduction reactions.
A common method for preparing 2-(Di-t-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine is by introducing a phosphine and diethylamine group on the aminomethyl group on pyridine. This can be obtained by reacting pyridine with diethylamine and di-tert-butylphosphinecarboxaldehyde.
Regarding safety information, the 2-(Di-t-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine is generally safer under normal conditions of use. However, like most chemicals, precautions should be taken when using them. It can cause eye and skin irritation, so wear appropriate protective equipment (such as gloves, goggles and laboratory coats) and avoid inhalation or ingestion. Any work with this compound should follow proper laboratory practices.
Last Update：2024-04-10 22:29:15
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