Molecular Formula | C8H6N4OS |
Molar Mass | 206.22 |
Density | 1.500±0.06 g/cm3(Predicted) |
Melting Point | 291-293°C |
Solubility | DMSO: ≥8mg/mL |
Appearance | powder |
Color | white to tan |
pKa | 6.78±0.50(Predicted) |
Storage Condition | room temp |
Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
Hazard Symbols | Xn - Harmful |
Risk Codes | 22 - Harmful if swallowed |
WGK Germany | 3 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 4.849 ml | 24.246 ml | 48.492 ml |
5 mM | 0.97 ml | 4.849 ml | 9.698 ml |
10 mM | 0.485 ml | 2.425 ml | 4.849 ml |
5 mM | 0.097 ml | 0.485 ml | 0.97 ml |
biological activity | TGN-020 (compound 9) is a selective aquaporin 4 (AQP4) inhibitor, IC50 is 3.1 μm, which may have an inhibitory effect on diabetic retinal edema. |