N-(1,3-benzodioxol-5-ylmethyl)-2-cyano-ethanamide
N-(1,3-Benzodioxol-5-ylmethyl)-2-cyanoacetamide
CAS: 341953-72-8
Molecular Formula: C11H10N2O3
N-(1,3-benzodioxol-5-ylmethyl)-2-cyano-ethanamide - Names and Identifiers
N-(1,3-benzodioxol-5-ylmethyl)-2-cyano-ethanamide - Physico-chemical Properties
| Molecular Formula | C11H10N2O3 |
| Molar Mass | 218.21 |
| Density | 1.316±0.06 g/cm3(Predicted) |
| Melting Point | 121-123 |
| Boling Point | 498.2±45.0 °C(Predicted) |
| pKa | 5.39±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD01345888 |
N-(1,3-benzodioxol-5-ylmethyl)-2-cyano-ethanamide - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
N-(1,3-benzodioxol-5-ylmethyl)-2-cyano-ethanamide - Introduction
N-(1,3-benzodioxol-5-ylmethyl)-2-cyanoacetamide is an organic compound with the chemical formula C11H9N3O3. It is a white crystal or crystalline powder with a special aromatic smell.
N-(1,3-Benzodioxol-5-ylmethyl)-2-cyanoacetamide has certain applications in chemical research and drug development. It is a commonly used intermediate and plays an important role in the synthesis of pesticides, pharmaceuticals and organic synthesis.
The method for preparing N-(1,3-Benzodioxol-5-ylmethyl)-2-cyanoacetamide can be obtained by reacting 1,3-benzenedioxoglutaric acid and chloroacetonitrile. The specific preparation steps are as follows:
1. Add 1,3-benzenedioxoglutaric acid and chloroacetonitrile to the reaction flask according to a certain molar ratio.
2. Start heating the reaction flask, control the reaction temperature within a suitable range, and stir the reactants.
3. After completion of the reaction, the reactant was filtered and washed.
4. The target product is obtained by crystallization and drying.
When using N-(1,3-Benzodioxol-5-ylmethyl)-2-cyanoacetamide, pay attention to its safety information. It is an organic compound that has a certain toxicity and can cause irritation and sensitive reactions. Wear appropriate protective equipment such as lab gloves, goggles, and protective clothing during operation. Avoid contact with skin, eyes and respiratory tract, and store in a cool, dry and well-ventilated place.
N-(1,3-Benzodioxol-5-ylmethyl)-2-cyanoacetamide has certain applications in chemical research and drug development. It is a commonly used intermediate and plays an important role in the synthesis of pesticides, pharmaceuticals and organic synthesis.
The method for preparing N-(1,3-Benzodioxol-5-ylmethyl)-2-cyanoacetamide can be obtained by reacting 1,3-benzenedioxoglutaric acid and chloroacetonitrile. The specific preparation steps are as follows:
1. Add 1,3-benzenedioxoglutaric acid and chloroacetonitrile to the reaction flask according to a certain molar ratio.
2. Start heating the reaction flask, control the reaction temperature within a suitable range, and stir the reactants.
3. After completion of the reaction, the reactant was filtered and washed.
4. The target product is obtained by crystallization and drying.
When using N-(1,3-Benzodioxol-5-ylmethyl)-2-cyanoacetamide, pay attention to its safety information. It is an organic compound that has a certain toxicity and can cause irritation and sensitive reactions. Wear appropriate protective equipment such as lab gloves, goggles, and protective clothing during operation. Avoid contact with skin, eyes and respiratory tract, and store in a cool, dry and well-ventilated place.
Last Update：2024-04-09 18:58:34
