N-(2-METHYL-6-NITRO-PHENYL)-ACETAMIDE

N-(2-METHYL-6-NITRO-PHENYL)-ACETAMIDE - Names and Identifiers

Name	N-(2-methyl-6-nitrophenyl)acetamide
Synonyms	2'-Methyl-6'-nitroacetanilide 6'-NITRO-ORTHO-ACETOTOLUIDIDE N-(2-methyl-6-nitrophenyl)acetamide N-(2-METHYL-6-NITRO-PHENYL)-ACETAMIDE Acetamide, N-(2-methyl-6-nitrophenyl)- 4-(4-chlorophenoxy)-3,5-difluorobenzene-1-sulfonyl chloride
CAS	59907-22-1
InChI	InChI=1/C9H10N2O3/c1-6-4-3-5-8(11(13)14)9(6)10-7(2)12/h3-5H,1-2H3,(H,10,12)

N-(2-METHYL-6-NITRO-PHENYL)-ACETAMIDE - Physico-chemical Properties

Molecular Formula	C9H10N2O3
Molar Mass	194.19
Density	1.289g/cm³
Boling Point	375.3°C at 760 mmHg
Flash Point	180.8°C
Vapor Presure	7.87E-06mmHg at 25°C
Storage Condition	2-8℃
Refractive Index	1.605

N-(2-METHYL-6-NITRO-PHENYL)-ACETAMIDE - Introduction

N-(2-methyl-6-nitrophenyl)acetamide is an organic compound with the chemical formula C9H10N2O3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: N-(2-methyl-6-nitrophenyl)acetamide is a yellow crystalline solid.
-Melting point: about 156-158 degrees Celsius.
-Solubility: Soluble in some organic solvents, such as chloroform and dimethyl sulfoxide, slightly soluble in ethanol and ether, almost insoluble in water.

Use:
- N-(2-methyl-6-nitrophenyl)acetamide is mainly used as a pharmaceutical intermediate for the synthesis of biologically active compounds.
-It can also be used in the preparation of organic optoelectronic materials, such as organic optoelectronic molecular devices and organic photoelectric conversion devices.

Preparation Method:
N-(2-methyl-6-nitrophenyl)acetamide has many preparation methods. The following is one of the commonly used methods:
-First, 2-methyl-6-nitrobenzyl alcohol is reacted with acetic anhydride to obtain acetic anhydride -2-methyl -6-nitrobenzoyl ester.
-Then, under alkaline conditions, acetic anhydride -2-methyl-6-nitrobenzoyl ester is oxidized to the corresponding acid with ethanol oxidizing agent, and then acylated with acetyl chloride to obtain N-(2-methyl-6-nitrophenyl)acetamide.
-Finally, the target product is purified by crystallization.

Safety Information:
- N-(2-methyl-6-nitrophenyl)acetamide should avoid contact with skin and eyes. Rinse with plenty of water immediately after contact.
-When using or storing, please follow the correct laboratory safety procedures.
-Due to the lack of sufficient toxicity data and evaluation, its toxic potential is not clear. Therefore, protective measures should be taken to avoid potential harm to personnel and the environment.
-When storing and handling the compound, avoid ignition and avoid contact with flammable substances such as oxidizing agents and reducing agents.

Last Update：2024-04-09 21:04:16