N-(3,5-Dichloropyridin-4-yl)-8-methoxyquinoline-5-carboxamide - Names and Identifiers
N-(3,5-Dichloropyridin-4-yl)-8-methoxyquinoline-5-carboxamide - Physico-chemical Properties
Molecular Formula | C16H11Cl2N3O2
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Molar Mass | 348.18 |
Density | 1.470±0.06 g/cm3(Predicted) |
Boling Point | 444.2±45.0 °C(Predicted) |
Flash Point | 198.192°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 9.21±0.70(Predicted) |
Storage Condition | 2-8℃ |
Refractive Index | 1.648 |
N-(3,5-Dichloropyridin-4-yl)-8-methoxyquinoline-5-carboxamide - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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HS Code | 29339900 |
N-(3,5-Dichloropyridin-4-yl)-8-methoxyquinoline-5-carboxamide - Introduction
acid is an organic compound with the formula C11H9NO3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: acid is a white crystalline solid.
-Solubility: Soluble in some organic solvents such as ether, chloroform and dimethyl sulfoxide, but insoluble in water.
-Chemical properties: The compound has a formic acid group and quinoline ring structure, and has a certain acidity.
Use:
-acid, as an intermediate in organic synthesis, has a wide range of applications in the fields of medicine, pesticides and dyes. It is an important raw material for the synthesis of quinolones, which have a broad spectrum of antibacterial and antiparasitic activities, so they are widely used in drug development.
Method:
The common synthesis method of acid is to use quinoline-5-carboxylic acid and methanol for esterification. First, Quinoline -5-formic acid and methanol are added into the reactor, and the esterification reaction is carried out under the action of acid catalyst to produce acid.
Safety Information:
-or acid is a chemical, be sure to pay attention to safe operation. Wear appropriate personal protective equipment such as lab gloves, goggles, and lab coats.
-Avoid contact with skin and eyes. If there is contact, rinse immediately with plenty of water for at least 15 minutes, and seek medical attention in time.
-When performing laboratory synthesis, place it in a well-ventilated place to avoid breathing its vapor.
-Storage should be sealed, dry, and away from fire and oxidizing agents.
Last Update:2024-04-09 21:01:54