N-(3-(3-Hydroxyprop-1-ynyl)pyridin-2-yl)pivalamide
N-(3-(3-Hydroxyprop-1-ynyl)pyridin-2-yl)pivalamide
CAS: 1203499-45-9
Molecular Formula: C13H16N2O2
N-(3-(3-Hydroxyprop-1-ynyl)pyridin-2-yl)pivalamide - Names and Identifiers
N-(3-(3-Hydroxyprop-1-ynyl)pyridin-2-yl)pivalamide - Physico-chemical Properties
| Molecular Formula | C13H16N2O2 |
| Molar Mass | 232.28 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD13563042 |
N-(3-(3-Hydroxyprop-1-ynyl)pyridin-2-yl)pivalamide - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Class | IRRITANT |
N-(3-(3-Hydroxyprop-1-ynyl)pyridin-2-yl)pivalamide - Introduction
N-(3-(3-Hydroxyprop-1-ynyl)pyridin-2-yl)pivalamide(N-(3-(3-hydroxyprop-1-ynyl) pyridin-2-yl) acetamide) is an organic compound. Its nature, use, method and safety information are as follows:
Nature:
-Appearance: Colorless or light yellow crystal.
-Molecular formula: C14H15N3O2.
-Molecular weight: 257.29g/mol.
-Melting point: 101-103°C.
-Solubility: Soluble in organic solvents such as dichloromethane and dimethyl sulfoxide.
Use:
N-(3-(3-hydroxyprop-1-ynyl) pyridin-2-yl) acetamide is a pesticide intermediate and organic synthesis reagent. It can be used in the synthesis of new heterocyclic compounds, pharmaceutical active compounds and organic light-emitting materials.
Preparation Method:
The preparation of N-(3-(3-hydroxyprop-1-ynyl) pyridin-2-yl) acetamide is usually carried out by the following steps:
1. Synthesis of 2-(pyridin-2-yl) ethanol: pyridine is reacted with vinyl magnesium bromide, and then hydrolyzed with acid.
2. Synthesis of N-(3-(3-hydroxyprop-1-ynyl) pyridin-2-yl) acetamide: 2-(pyridin-2-yl) ethanol is reacted with p-sec-butyl bromide acetamide, followed by base hydrolysis.
Safety Information:
For specific safety information on N-(3-(3-hydroxyprop-1-ynyl) pyridin-2-yl) acetamide, please refer to the safety data sheet (SDS) of the product. When using or handling this compound, follow laboratory safety practices, including wearing appropriate personal protective equipment, such as lab gloves and safety glasses. In addition, avoid contact with skin and eyes to prevent inhalation or ingestion.
Nature:
-Appearance: Colorless or light yellow crystal.
-Molecular formula: C14H15N3O2.
-Molecular weight: 257.29g/mol.
-Melting point: 101-103°C.
-Solubility: Soluble in organic solvents such as dichloromethane and dimethyl sulfoxide.
Use:
N-(3-(3-hydroxyprop-1-ynyl) pyridin-2-yl) acetamide is a pesticide intermediate and organic synthesis reagent. It can be used in the synthesis of new heterocyclic compounds, pharmaceutical active compounds and organic light-emitting materials.
Preparation Method:
The preparation of N-(3-(3-hydroxyprop-1-ynyl) pyridin-2-yl) acetamide is usually carried out by the following steps:
1. Synthesis of 2-(pyridin-2-yl) ethanol: pyridine is reacted with vinyl magnesium bromide, and then hydrolyzed with acid.
2. Synthesis of N-(3-(3-hydroxyprop-1-ynyl) pyridin-2-yl) acetamide: 2-(pyridin-2-yl) ethanol is reacted with p-sec-butyl bromide acetamide, followed by base hydrolysis.
Safety Information:
For specific safety information on N-(3-(3-hydroxyprop-1-ynyl) pyridin-2-yl) acetamide, please refer to the safety data sheet (SDS) of the product. When using or handling this compound, follow laboratory safety practices, including wearing appropriate personal protective equipment, such as lab gloves and safety glasses. In addition, avoid contact with skin and eyes to prevent inhalation or ingestion.
Last Update：2024-04-09 20:52:54
