N-(3-Hydroxy-2-iodopyridin-4-yl)pivalamide
N-(3-Hydroxy-2-iodopyridin-4-yl)pivalamide
CAS: 1142192-39-9
Molecular Formula: C10H13IN2O2
N-(3-Hydroxy-2-iodopyridin-4-yl)pivalamide - Names and Identifiers
| Name | N-(3-Hydroxy-2-iodopyridin-4-yl)pivalamide |
| Synonyms | N-(3-Hydroxy-2-iodopyridin-4-yl)pivalamide Propanamide, N-(3-hydroxy-2-iodo-4-pyridinyl)-2,2-dimethyl- |
| CAS | 1142192-39-9 |
N-(3-Hydroxy-2-iodopyridin-4-yl)pivalamide - Physico-chemical Properties
| Molecular Formula | C10H13IN2O2 |
| Molar Mass | 320.13 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD12026759 |
N-(3-Hydroxy-2-iodopyridin-4-yl)pivalamide - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Class | IRRITANT |
N-(3-Hydroxy-2-iodopyridin-4-yl)pivalamide - Introduction
N-(aryl) pivalamide(N-(3-hydroxy-2-iodopyridin-4-yl) pentanediamide) is an organic compound. It is a white solid with the chemical formula C12H15IN2O2. The following is a description of the properties, use, preparation and safety information of the compound:
Nature:
N-pivalamide have the following properties:
-Appearance: White solid
-Molecular weight: 314.17g/mol
-Melting point: about 120-122°C
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dimethyl sulfoxide
-Stability: relatively stable under normal storage and use conditions
Use:
N-(pivalamide) has certain application value in chemical synthesis, including:
-as an intermediate or raw material in organic synthesis, used in the synthesis of other organic compounds;
-can be used to synthesize biologically active compounds, such as drugs, pesticides and dyes.
Preparation Method:
The preparation of N-(pivalamide) can be carried out by the following reactions:
-First, 2-iodo-3-hydroxypyridine is reacted with glutaryl chloride to generate 2-iodo-3-hydroxypyridine-4-carbonyl chloride compound;
-Then, 2-iodo-3-hydroxypyridine-4-carbonyl chloride reacts with piperazine to generate N-(r) pivalamide.
Safety Information:
There is very limited safety data on N-pivalamide. As a chemical, the following general safety practices should be followed when used:
-Avoid contact with skin, eyes and respiratory tract, and wear appropriate protective equipment (such as gloves, goggles and protective masks) when used;
-Avoid inhaling dust or gas, and the operation should be carried out in a well-ventilated place;
-Avoid contact with strong oxidants and acids, and store in a dry, ventilated and dark place.
Due to the lack of relevant toxicity and safety data, specific safe operations should be determined according to specific conditions and laboratory facilities, and local regulations should be followed. It is strongly recommended to consult reliable chemical safety data and operational guidelines prior to use.
Nature:
N-pivalamide have the following properties:
-Appearance: White solid
-Molecular weight: 314.17g/mol
-Melting point: about 120-122°C
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dimethyl sulfoxide
-Stability: relatively stable under normal storage and use conditions
Use:
N-(pivalamide) has certain application value in chemical synthesis, including:
-as an intermediate or raw material in organic synthesis, used in the synthesis of other organic compounds;
-can be used to synthesize biologically active compounds, such as drugs, pesticides and dyes.
Preparation Method:
The preparation of N-(pivalamide) can be carried out by the following reactions:
-First, 2-iodo-3-hydroxypyridine is reacted with glutaryl chloride to generate 2-iodo-3-hydroxypyridine-4-carbonyl chloride compound;
-Then, 2-iodo-3-hydroxypyridine-4-carbonyl chloride reacts with piperazine to generate N-(r) pivalamide.
Safety Information:
There is very limited safety data on N-pivalamide. As a chemical, the following general safety practices should be followed when used:
-Avoid contact with skin, eyes and respiratory tract, and wear appropriate protective equipment (such as gloves, goggles and protective masks) when used;
-Avoid inhaling dust or gas, and the operation should be carried out in a well-ventilated place;
-Avoid contact with strong oxidants and acids, and store in a dry, ventilated and dark place.
Due to the lack of relevant toxicity and safety data, specific safe operations should be determined according to specific conditions and laboratory facilities, and local regulations should be followed. It is strongly recommended to consult reliable chemical safety data and operational guidelines prior to use.
Last Update：2024-04-09 21:01:54
