N-(3-Hydroxypropyl)benzylamine - Names and Identifiers
N-(3-Hydroxypropyl)benzylamine - Physico-chemical Properties
Molecular Formula | C10H15NO
|
Molar Mass | 165.23 |
Density | 1.022±0.06 g/cm3(Predicted) |
Boling Point | 115°C/0.7mmHg(lit.) |
Flash Point | 117.9°C |
Solubility | Chloroform, Dichloromethane, Ethyl Acetate |
Vapor Presure | 0.000991mmHg at 25°C |
Appearance | Oil |
Color | Colorless |
pKa | 14.96±0.10(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.5360-1.5400 |
N-(3-Hydroxypropyl)benzylamine - Introduction
3-Benzylamino-1-propanol is an organic compound with the chemical formula C10H15NO. The following is a description of its nature, use, preparation and safety information:
Nature:
3-Benzylamino-1-propanol is a colorless to slightly yellow liquid with a benzene fragrance. It is easily soluble in ethanol, chloroform and acetone, slightly soluble in water. It is alkaline and can react with acids to form the corresponding salts.
Use:
3-Benzylamino-1-propanol is widely used in the field of organic synthesis. It is an important intermediate for the preparation of pharmaceuticals and other organic compounds. It is commonly used in the synthesis of peptides, protein inhibitors, heterocyclic compounds and other natural products.
Preparation Method:
3-Benzylamino-1-propanol can be formed by reacting benzylamine with propionaldehyde. The specific synthesis method is as follows:
1. Add appropriate amount of benzylamine and propionaldehyde in the reaction flask.
2. Add a catalyst, usually copper acetate, etc.
3. The reaction is carried out at an appropriate temperature, and the common solvent is methanol or dimethyl sulfoxide.
4. After completion of the reaction, separation and purification are carried out to obtain the target product.
Safety Information:
3-Benzylamino-1-propanol is an organic compound that is toxic and corrosive. Personal protective equipment such as chemical protective gloves, goggles and protective clothing should be worn during use. Avoid contact with eyes, skin and respiratory tract. During operation, it should be kept away from open flames and high temperatures. Store away from oxidants and acids, and store in a cool, dry, well-ventilated place.
Last Update:2024-04-09 02:00:46