N-(3-methoxybenzyl)aniline
N-[(3-methoxyphenyl)methyl]aniline
CAS: 81308-21-6
Molecular Formula: C14H15NO
N-(3-methoxybenzyl)aniline - Names and Identifiers
N-(3-methoxybenzyl)aniline - Physico-chemical Properties
| Molecular Formula | C14H15NO |
| Molar Mass | 213.27 |
N-(3-methoxybenzyl)aniline - Introduction
N-[(3-methoxyphenyl)methyl]aniline is an organic compound with the chemical formula C14H15NO. Its nature is as follows:
1. Appearance: N-[(3-methoxyphenyl)methyl]aniline is a white to pale yellow crystalline solid.
2. Solubility: It can be dissolved in organic solvents such as ethanol, chloroform, dimethylformamide and dichloromethane, but its solubility in water is low.
3. odor: it has the characteristic ammonia odor of aniline.
4. Melting point: The melting point of N-[(3-methoxyphenyl)methyl]aniline is about 80-82°C.
The compound is mainly used in organic synthesis and has the following applications:
1. Drug synthesis: N-[(3-methoxyphenyl)methyl]aniline can be used as an intermediate for the synthesis of other drugs or compounds. For example, it can be used in the synthesis of anti-tumor drugs.
2. Dye synthesis: It is also a raw material for some dyes and can be used to synthesize pigments or dyes.
Preparation method of N-[(3-methoxyphenyl)methyl]aniline:
1. The digermer-allyl piperidine reaction through benzylamine: the benzylamine is reacted with 3-chloropropene piperidine, and then methanol is added under alkaline conditions to generate N-[(3-methoxyphenyl)methyl]aniline.
2. by methanation of aromatic amines: N-phenylbenzylamine reacts with methanol under the catalysis of hydrochloric acid to generate N-[(3-methoxyphenyl)methyl]aniline.
Regarding its safety information, N-[(3-methoxyphenyl)methyl]aniline is a chemical that should be handled and stored properly. According to the relevant safety data sheet, it may be irritating and toxic, and contact with skin, eyes and respiratory tract should be avoided. Wear appropriate personal protective equipment during use and ensure that you operate in a well-ventilated area.
1. Appearance: N-[(3-methoxyphenyl)methyl]aniline is a white to pale yellow crystalline solid.
2. Solubility: It can be dissolved in organic solvents such as ethanol, chloroform, dimethylformamide and dichloromethane, but its solubility in water is low.
3. odor: it has the characteristic ammonia odor of aniline.
4. Melting point: The melting point of N-[(3-methoxyphenyl)methyl]aniline is about 80-82°C.
The compound is mainly used in organic synthesis and has the following applications:
1. Drug synthesis: N-[(3-methoxyphenyl)methyl]aniline can be used as an intermediate for the synthesis of other drugs or compounds. For example, it can be used in the synthesis of anti-tumor drugs.
2. Dye synthesis: It is also a raw material for some dyes and can be used to synthesize pigments or dyes.
Preparation method of N-[(3-methoxyphenyl)methyl]aniline:
1. The digermer-allyl piperidine reaction through benzylamine: the benzylamine is reacted with 3-chloropropene piperidine, and then methanol is added under alkaline conditions to generate N-[(3-methoxyphenyl)methyl]aniline.
2. by methanation of aromatic amines: N-phenylbenzylamine reacts with methanol under the catalysis of hydrochloric acid to generate N-[(3-methoxyphenyl)methyl]aniline.
Regarding its safety information, N-[(3-methoxyphenyl)methyl]aniline is a chemical that should be handled and stored properly. According to the relevant safety data sheet, it may be irritating and toxic, and contact with skin, eyes and respiratory tract should be avoided. Wear appropriate personal protective equipment during use and ensure that you operate in a well-ventilated area.
Last Update：2024-04-09 21:54:55
