N-(3α,6α,7α-Trihydroxy-24-oxo-5β-cholan-24-yl)glycine - Names and Identifiers
Name | Glycohyocholic acid
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Synonyms | Glycohyocholic acid Glycohyocholic acid (GHCA) N-(24-Oxo-3α,6α,7α-trihydroxy-5β-cholan-24-yl)glycine N-(3α,6α,7α-Trihydroxy-24-oxo-5β-cholan-24-yl)glycine Glycine, N-[(3α,5β,6α,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]- 2-[[(4R)-4-[(3R,5R,6R,7S,8S,9S,10R,13R,14S,17R)-3,6,7-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
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CAS | 32747-08-3
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N-(3α,6α,7α-Trihydroxy-24-oxo-5β-cholan-24-yl)glycine - Physico-chemical Properties
Molecular Formula | C26H43NO6
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Molar Mass | 465.63 |
Density | 1.213±0.06 g/cm3(Predicted) |
Boling Point | 673.4±55.0 °C(Predicted) |
pKa | 3.58±0.10(Predicted) |
Storage Condition | -20°C |
N-(3α,6α,7α-Trihydroxy-24-oxo-5β-cholan-24-yl)glycine - Introduction
Open Data Unverified Data
Glycohyocholic acid (Glycocholic acid) is a biological bile acid, also known as 3α, 6α-dihydroxy-5β-cholic acid. It is a combination of cholic acid and glycine, and plays an important physiological function in bile in the human body. Glycohyocholic acid is a white crystalline solid that is soluble in water and alcoholic solvents.
Glycohyocholic acid has many uses. First, it is an important intermediate for drug research and preparation. Secondly, it is used in the detection of biliary and liver diseases in clinical diagnosis. In addition, Glycohyocholic acid is also used in the design of drug delivery systems to improve drug solubility and bioavailability.
There are two main methods for preparing Glycohyocholic acid. One is an esterification reaction using cholic acid with glycine to produce Glycohyocholic acid. Another method is the Amination of cholic acid compounds with glycine to produce Glycohyocholic acid.
Regarding safety information, Glycohyocholic acid is generally considered safe, but caution is still required when using and handling it. It may cause irritation to the skin, eyes and respiratory tract, so proper protective measures such as gloves and goggles are required during operation. In addition, it is also necessary to follow the relevant safety procedures and store it in a dry and cool place, away from fire and flammable materials. When using Glycohyocholic acid, be sure to follow the relevant instructions for use and laboratory safety regulations. In case of further doubt, it is recommended to seek professional advice.
Last Update:2024-04-09 19:43:38