N-(4,6-dimethylpyrimidin-2-yl)aniline
pyrimethanil
CAS: 53112-28-0
Molecular Formula: C12H13N3
N-(4,6-dimethylpyrimidin-2-yl)aniline - Names and Identifiers
| Name | pyrimethanil |
| Synonyms | Mytho Hsdb 6916 Dynmethanil pyrimethanil Pyrimethanil [iso] Pyrimethanil Standard PYRIMETHANIL PESTANAL, 250 MG N-(4,6-dimethylpyrimidin-2-yl)aniline 4,6-dimethyl-N-phenylpyrimidin-2-amine 4,6-Dimethyl-N-phenyl-2-pyrimidinamine 2-Pyrimidinamine, 4,6-dimethyl-N-phenyl- 4,6-DIMETHYL-N-PHENYL-2-PYRIMIDINAMINE(PYRIMETHANIL) |
| CAS | 53112-28-0 |
| EINECS | 414-220-3 |
| InChI | InChI=1/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) |
N-(4,6-dimethylpyrimidin-2-yl)aniline - Physico-chemical Properties
| Molecular Formula | C12H13N3 |
| Molar Mass | 199.25 |
| Density | 1.15 |
| Melting Point | 96°C |
| Boling Point | 362.8±45.0 °C(Predicted) |
| Flash Point | 173.2°C |
| Water Solubility | 0.121 g/L (25 ºC) |
| Vapor Presure | 2.2 x l0-5 Pa (25 °C) |
| Appearance | neat |
| BRN | 151589 |
| pKa | 3.52 |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.622 |
| Physical and Chemical Properties | Density 1.15 melting point 96°C water-soluble 0.121g/L (25°C) |
| Use | For the prevention and control of cucumber, tomato, grape, strawberry, pea, leek and other crops gray mold, fruit tree scab, spot leaf disease, etc |
N-(4,6-dimethylpyrimidin-2-yl)aniline - Risk and Safety
| Hazard Symbols | N - Dangerous for the environment |
| Risk Codes | 51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | 60 - This material and its container must be disposed of as hazardous waste. |
| UN IDs | UN 3077 |
| WGK Germany | 2 |
| Toxicity | LD50 (mg/kg): 4061-5358 orally in mice; 4150-5971 orally in rats; >5000 dermally in rats; LC50 (96 hr) in mirror carp, rainbow trout (mg/l): 35.36, 10.56 (Neumann) |
N-(4,6-dimethylpyrimidin-2-yl)aniline - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Fungicide | Pyrimethanil (pyrimethanil), also known as methylpyrimidine and dimethylpyrimidine, belongs to phenylaminopyrimidine fungicides and has special effects on gray mold. Pyrimethanil was reported by GL.Neumann et al. (Proc.Br.Crop Prot.Conf.-Pests Dis.,1992,1:395), discovered and developed by ScheringAG and Hoechst Schering AgrEvo, and is now owned by Bayer CropScience. In Europe, it was divested to BASF AG (now BASF SE) in 2003. Its bactericidal mechanism is unique. By inhibiting the secretion of bacteria-infecting enzymes, it prevents bacteria from infecting, thereby killing bacteria. It has protective and therapeutic effects, as well as internal absorption and fumigation effects. Pyrimethanil has the function of inhibiting the secretion of fungal pathogen-infected enzymes, and can quickly penetrate into plant tissues and conduct in surface tissues. It is a fungicide characterized by protective effect, treatment of latent infection of bacteria and inhibition of disease expansion, and has a certain fumigation effect; it can effectively prevent and control cucumber gray mold. |
| effect | pyrimethanil has a strong systemic conduction effect, and can quickly run to the parts of the plant where drugs such as flowers and young fruits cannot be sprayed, thereby killing Botrytis cinerea. At the same time, it is not sensitive to the outside temperature, and the application effect in winter and spring is still fast and stable. In production, pyrimethanil is not only widely used in cucumbers, tomatoes and other fruits and vegetables, but also has a wonderful effect in controlling gray mold of grapes. |
| toxicity | mammalian toxicity acute oral: LD50(mg/kg); Rats 4 150~5 971, mice 4 665~5 359. Acute percutaneous LD50>5 000 mg/kg in rats. No irritation to rabbit skin and eyes. Non-guinea pig skin sensitizer. Rats inhaled LC50(4 h)>1.98 mg/L. NOEL(90 d) rats 5.4 mg/(kg • d);(2 years) rats 17 mg/(kg • d)(EFSA Sci.Rep.). ADI/RfD(JMPR)0.2 mg/kg;(EC)0.17 mg/kg;(EPA)0.2 mg/kg. It has no mutagenicity or teratogenicity to rats and rabbits. Toxicity grade: U(a. I., who);Ⅳ(Scala and Mythos)(preparation, EPA). EC classification: N;R51,R53. Ecotoxicity mallard and mallard quail acute oral LD50>2 000 mg/kg. Mallard and mallard quail acute oral LC50(5 d)>5 200 mg/kg feed. Mirror carp LC50(96 h)35.4, rainbow trout 10.6 mg/L. Daphnia LC50(48 h)2.9 mg/L. Algae EbC50(96 h)1.2 mg/L,ErC50(96 h)5.84 mg/L. Honeybee LD50 (oral and contact)>100 μm/mouse. Earthworm LC50(14 d)625 mg/kg dry soil. Under better field farming conditions, there was no effect on non-target arthropods. |
| control object | pyrimethanil is used to control gray mold, fusarium wilt, fruit tree scab, spotted defoliation, etc. of crops such as leeks, cucumbers, tomatoes, grapes, strawberries, peas, etc. It prevents gray mold (Botrytis cinerea) on grapes with an application rate of 500~1,000g/hm2; For soft fruits, such as strawberry gray mold, the application amount is 800~1000g/hm2; For vegetables, such as cucumber gray mold and leek gray mold, the application amount of 40% pyrimethanil is 80~95 mL/mu and 50~75 mL/mu respectively; For ornamental plants, such as ornamental chrysanthemum, spray with 80% pyrimethanil 1000~2000 times. To control scab disease (apple scab or pear scab) of fruits and leaves of kernel fruit, the application amount is 300~450g/hm2. Apple pre-harvest treatment to control Penicillium, the application rate of 80g/hm2. When spraying in glass and plastic greenhouses, relative humidity> 80% is recommended, and ventilation equipment is installed to avoid leaf spots on some crops. |
| use | pyrimethanil is a pyrimidine fungicide, which has leaf penetration and root absorption activity, and has excellent control effect on gray mold of grapes, strawberries, tomatoes, onions, kidney beans, cucumbers, eggplants and ornamental plants. It also has a good control effect on apple black fishy disease in fruit trees. used to prevent and control gray mold of cucumber, tomato, grape, strawberry, pea, leek and other crops, fruit tree scab, spot defoliation, etc. used as a specific medicine for controlling gray mold |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 21:11:58
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Product Name: Pyrimethanil Visit Supplier Webpage Request for quotationCAS: 53112-28-0
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Mobile: 18021002903
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Wechat: 18301782025
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