N-(4-Amino-m-tolyl)-N-ethylbenzamide

N-(4-Amino-m-tolyl)-N-ethylbenzamide - Names and Identifiers

Name	N-(4-amino-m-tolyl)-N-ethylbenzamide
Synonyms	N-(4-Amino-m-tolyl)-N-ethylbenzamide N-(4-amino-m-tolyl)-N-ethylbenzamide 4-AMINO-3-METHYL-N-ETHYL BENZANILIDE 3'-methyl-4'-amino-N-ethylbenzanilide 4-amino-2-ethyl-3-methyl-N-phenylbenzamide 4-(N-Ethyl-N-benzoylamino)-2-methylaniline N-(4-amino-3-methylphenyl)-N-ethylbenzamide N-(4-AMINO-3-METHYLPHENYL)-N-ETHYLBENZAMIDE N-(4-azanyl-3-methyl-phenyl)-N-ethyl-benzamide
CAS	5856-00-8
EINECS	227-473-8
InChI	InChI=1/C16H18N2O/c1-3-18(14-9-10-15(17)12(2)11-14)16(19)13-7-5-4-6-8-13/h4-11H,3,17H2,1-2H3

N-(4-Amino-m-tolyl)-N-ethylbenzamide - Physico-chemical Properties

Molecular Formula	C16H18N2O
Molar Mass	254.33
Density	1.146g/cm³
Boling Point	455.3°C at 760 mmHg
Flash Point	229.2°C
Vapor Presure	1.77E-08mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.632

N-(4-Amino-m-tolyl)-N-ethylbenzamide - Introduction

N-(4-amino-m-tolyl)-N-ethylbenzamide is an organic compound with the chemical formula C16H19N2O. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: N-(4-amino-m-tolyl)-N-ethylbenzamide is a white crystalline solid.
-Solubility: It is soluble in alcohol and ketone solvents, but insoluble in water.
-Melting point: Its melting point is between 75-77°C.

Use:
- N-(4-amino-m-tolyl)-N-ethylbenzamide is a pharmaceutical intermediate commonly used to prepare other pharmaceutical compounds.
-It can also be used as a potential tumor suppressor.

Preparation Method:
N-(4-amino-m-tolyl)-N-ethylbenzamide can be obtained by the following synthetic route:
1. reacting p-methylbenzoyl chloride with ethylamine to give N-(ethylbenzoyl)-4-methylaminobenzene (N-ethylbenzamide-4-methylaniline).
2. Through a reduction reaction, 4-methylaminobenzene (4-methylaniline) is converted into 4-amino-3-methylaniline (4-amino-m-toluidine) using a suitable reducing agent to obtain the final product N-(4-amino-m-tolyl)-N-ethylbenzamide.

Safety Information:
- N-(4-amino-m-tolyl)-N-ethylbenzamide safety and toxicity data are relatively limited, so appropriate laboratory safety operations and personal protective measures should be followed when using or handling.
-Avoid direct contact with the substance in the eyes, skin and respiratory tract. In case of accidental contact, rinse with water or seek medical help.
-When storing and handling this compound, observe relevant safety guidelines and regulatory requirements.

Last Update：2024-04-09 20:49:11