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N-(4-CHLOROPHENYL)UREA

4-Chlorophenylurea

CAS: 140-38-5

Molecular Formula: C7H7ClN2O

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N-(4-CHLOROPHENYL)UREA - Names and Identifiers

Name 4-Chlorophenylurea
Synonyms p-CPU
AI3-20197
NSC 12971
BRN 0908492
4-Chlorophenylurea
P-CHLOROPHENYL UREA
(p-Chlorophenyl)urea
(4-Chlorophenyl)urea
1-(4-chlorophenyl)urea
1-(p-Chlorophenyl)urea
N-(4-CHLOROPHENYL)UREA
1-(p-chlorophenyl)-ure
Urea, (p-chlorophenyl)-
Urea, (4-chlorophenyl)-
Urea, 1-(p-chlorophenyl)-
CHLORHEXIDINE EP IMPURITY F
Urea, (p-chlorophenyl)- (8CI)
4-12-00-01191 (Beilstein Handbook Reference)
CAS 140-38-5
EINECS 205-412-6
InChI InChI=1/C7H7ClN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)

N-(4-CHLOROPHENYL)UREA - Physico-chemical Properties

Molecular FormulaC7H7ClN2O
Molar Mass170.6
Density1.402±0.06 g/cm3(Predicted)
Melting Point204-205°C
Boling Point271.7±23.0 °C(Predicted)
Flash Point118.1°C
Vapor Presure0.00634mmHg at 25°C
AppearanceWhite crystalline powder
BRN908492
pKa14.13±0.70(Predicted)
Storage ConditionRoom Temprature
Refractive Index1.649
MDLMFCD00014788
Physical and Chemical PropertiesChlorophenyl urea pure colorless crystals, m. P. 210 ℃ (decomposition), insoluble in water, soluble in ethanol.

N-(4-CHLOROPHENYL)UREA - Risk and Safety

Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
RTECSYS6127000
Hazard ClassIRRITANT

N-(4-CHLOROPHENYL)UREA - Reference Information

NIST chemical information Information provided by: webbook.nist.gov (external link)
EPA chemical information Information provided by: ofmpub.epa.gov (external link)
Use p-chlorophenylurea is an intermediate for the synthesis of dichloramide by the non-phosgene route (sodium cyanate method).
Production method The preparation method is to obtain p-chlorophenylurea by reacting p-chloroaniline hydrochloride with sodium cyanate. A certain amount of p-chloroaniline, concentrated hydrochloric acid and water are sequentially added to the reaction kettle to dissolve it and cool it to room temperature. Dissolve the solid sodium cyanate in water in another reaction kettle and filter to obtain a colorless solution. Under stirring, the solution is gradually added to the reaction kettle containing p-chloroaniline hydrochloride, and the feeding temperature is controlled so that it does not exceed 30 ℃. After feeding, stir at 30 ℃ for 2h, filter, wash the solid with water for 2-3 times, and dry, that is, the product is p-chlorophenylurea.
Last Update:2024-04-09 02:00:06
N-(4-CHLOROPHENYL)UREA
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Email: Int06@meryer.com
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CAS: 140-38-5
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