N-(4-Formyl-2-methoxypyridin-3-yl)pivalamide
N-(4-Formyl-2-methoxypyridin-3-yl)pivalamide
CAS: 1142192-44-6
Molecular Formula: C12H16N2O3
N-(4-Formyl-2-methoxypyridin-3-yl)pivalamide - Names and Identifiers
| Name | N-(4-Formyl-2-methoxypyridin-3-yl)pivalamide |
| Synonyms | N-(4-Formyl-2-methoxypyridin-3-yl)pivalamide Propanamide, N-(4-formyl-2-methoxy-3-pyridinyl)-2,2-dimethyl- |
| CAS | 1142192-44-6 |
N-(4-Formyl-2-methoxypyridin-3-yl)pivalamide - Physico-chemical Properties
| Molecular Formula | C12H16N2O3 |
| Molar Mass | 236.27 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD12026763 |
N-(4-Formyl-2-methoxypyridin-3-yl)pivalamide - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
N-(4-Formyl-2-methoxypyridin-3-yl)pivalamide - Introduction
N-(aryl) pivalamide(N-(4-formyl-2-methoxypyridin-3-yl) oxime acetate) is an organic compound. Its molecular formula is C13H17N3O3 and its molecular weight is 263.29.
Properties of the compound include:
-Appearance: colorless or yellowish crystal
-Melting point: about 120-125 degrees Celsius
-Water soluble: Slightly soluble in water, soluble in organic solvents such as ethanol and dichloromethane
N-(Br) pivalamide has certain application value in organic synthesis:
-It can be used as an intermediate to synthesize other organic compounds, such as for the preparation of anti-cancer drugs or other biologically active substances.
The method of preparing N-(a pivalamide step) usually includes the following:
1. reacting 2-methoxy -4-bromopyridine with formamide to form N-(2-methoxy -4-pyridyl) formamide.
2. Esterification reaction using ethyl t-butoxycarbonylformate and acetic anhydride to produce ethyl N-(2-methoxy-4-pyridyl)-4-formylbutyrate.
3. Finally, the ester is hydrolyzed to N-(4-formyl-2-methoxypyridin-3-yl) oxime acetate under acidic conditions.
When using N-(over) pivalamide, you need to pay attention to its safety:
-This compound may cause irritation to the eyes, skin and respiratory tract, so wear appropriate protective equipment such as gloves, safety goggles and protective masks.
-Avoid inhalation or ingestion of the compound and maintain good ventilation.
-When handling this compound, follow laboratory safety practices and properly dispose of waste.
Properties of the compound include:
-Appearance: colorless or yellowish crystal
-Melting point: about 120-125 degrees Celsius
-Water soluble: Slightly soluble in water, soluble in organic solvents such as ethanol and dichloromethane
N-(Br) pivalamide has certain application value in organic synthesis:
-It can be used as an intermediate to synthesize other organic compounds, such as for the preparation of anti-cancer drugs or other biologically active substances.
The method of preparing N-(a pivalamide step) usually includes the following:
1. reacting 2-methoxy -4-bromopyridine with formamide to form N-(2-methoxy -4-pyridyl) formamide.
2. Esterification reaction using ethyl t-butoxycarbonylformate and acetic anhydride to produce ethyl N-(2-methoxy-4-pyridyl)-4-formylbutyrate.
3. Finally, the ester is hydrolyzed to N-(4-formyl-2-methoxypyridin-3-yl) oxime acetate under acidic conditions.
When using N-(over) pivalamide, you need to pay attention to its safety:
-This compound may cause irritation to the eyes, skin and respiratory tract, so wear appropriate protective equipment such as gloves, safety goggles and protective masks.
-Avoid inhalation or ingestion of the compound and maintain good ventilation.
-When handling this compound, follow laboratory safety practices and properly dispose of waste.
Last Update：2024-04-09 21:00:56
