N-(5-Amino-2-chlorophenyl)acetamide
N-(5-Amino-2-chlorophenyl)acetamide
CAS: 57946-67-5
Molecular Formula: C8H9ClN2O
N-(5-Amino-2-chlorophenyl)acetamide - Names and Identifiers
| Name | N-(5-Amino-2-chlorophenyl)acetamide |
| Synonyms | SKL625 N-(5-Amino-2-chlorophenyl)acetamide Acetamide, N-(5-amino-2-chlorophenyl)- |
| CAS | 57946-67-5 |
N-(5-Amino-2-chlorophenyl)acetamide - Physico-chemical Properties
| Molecular Formula | C8H9ClN2O |
| Molar Mass | 184.62 |
| Density | 1.350±0.06 g/cm3(Predicted) |
| Boling Point | 405.8±35.0 °C(Predicted) |
| pKa | 13.89±0.70(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD08691762 |
N-(5-Amino-2-chlorophenyl)acetamide - Introduction
N-(5-Amino-2-chlorophenyl)acetamide is an organic compound with the molecular formula C8H8ClNO, commonly abbreviated as AACA. The following is a description of the properties, uses, preparation and safety information of the compound:
1. nature:
-Appearance: White crystalline powder
-melting point: about 149-151 ℃
-Solubility: Soluble in alcohol, ether and chloroform, slightly soluble in water
2. use:
- N-(5-amino-2-chlorophenyl) acetamide has a wide range of applications and is often used as an intermediate or raw material for organic synthesis.
-It can be used in the field of medicine for the synthesis of antibacterial drugs, anticancer drugs and other bioactive molecules.
3. preparation method:
The preparation of-N-(5-amino-2-chlorophenyl) acetamide is usually accomplished by an aminolysis reaction. The specific steps include reacting 5-amino -2-chlorobenzoyl chloride (5-Amino-2-chlorobenzoyl chloride) with acetic acid urea to generate acetamide urea derivative. Then, the acetamide urea derivative is reacted with a base (e. g., sodium carbonate) to finally produce the target product N-(5-amino-2-chlorophenyl) acetamide.
4. Safety Information:
- N-(5-amino-2-chlorophenyl) acetamide is an organic compound and must be handled with care. During the operation, contact with skin, eyes and inhalation should be avoided.
-When in contact with the compound, rinse immediately with plenty of water and seek medical assistance.
-Observe safety procedures and personal protective measures when storing or handling the compound.
1. nature:
-Appearance: White crystalline powder
-melting point: about 149-151 ℃
-Solubility: Soluble in alcohol, ether and chloroform, slightly soluble in water
2. use:
- N-(5-amino-2-chlorophenyl) acetamide has a wide range of applications and is often used as an intermediate or raw material for organic synthesis.
-It can be used in the field of medicine for the synthesis of antibacterial drugs, anticancer drugs and other bioactive molecules.
3. preparation method:
The preparation of-N-(5-amino-2-chlorophenyl) acetamide is usually accomplished by an aminolysis reaction. The specific steps include reacting 5-amino -2-chlorobenzoyl chloride (5-Amino-2-chlorobenzoyl chloride) with acetic acid urea to generate acetamide urea derivative. Then, the acetamide urea derivative is reacted with a base (e. g., sodium carbonate) to finally produce the target product N-(5-amino-2-chlorophenyl) acetamide.
4. Safety Information:
- N-(5-amino-2-chlorophenyl) acetamide is an organic compound and must be handled with care. During the operation, contact with skin, eyes and inhalation should be avoided.
-When in contact with the compound, rinse immediately with plenty of water and seek medical assistance.
-Observe safety procedures and personal protective measures when storing or handling the compound.
Last Update：2024-04-09 02:00:57
