N-(5-BROMO-4-METHYL-PYRIDIN-2-YL)-ACETAMIDE

N-(5-BROMO-4-METHYL-PYRIDIN-2-YL)-ACETAMIDE - Names and Identifiers

Name	2-ACETAMIDO-4-METHYL-5-BROMOPYRIDINE
Synonyms	2-ACETAMIDO-5-BROMO-4-PICOLINE 2-Acetamido-5-bromo-gamma-picoline 2-ACETAMIDO-4-METHYL-5-BROMOPYRIDINE 2-Acetamido-5-bromo-4-methylpyridine 2-ACETYLAMINO-5-BROMO-4-METHYLPYRIDINE 2-Acetylamino-5-bromo-4-methylpyridine Acetamide,N-(5-bromo-4-methyl-2-pyridinyl)- N-(5-BROMO-4-METHYL-PYRIDIN-2-YL)-ACETAMIDE
CAS	142404-82-8
InChI	InChI=1/C8H9BrN2O/c1-5-3-8(11-6(2)12)10-4-7(5)9/h3-4H,1-2H3,(H,10,11,12)

N-(5-BROMO-4-METHYL-PYRIDIN-2-YL)-ACETAMIDE - Physico-chemical Properties

Molecular Formula	C8H9BrN2O
Molar Mass	229.07
Density	1.545
Melting Point	151-155 °C (lit.)
Boling Point	372.5±42.0 °C(Predicted)
Flash Point	179.1°C
Vapor Presure	9.6E-06mmHg at 25°C
pKa	12.94±0.70(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.606
Physical and Chemical Properties	WGK Germany:3

N-(5-BROMO-4-METHYL-PYRIDIN-2-YL)-ACETAMIDE - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R42/43 - May cause sensitization by inhalation and skin contact.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
HS Code	29333990

N-(5-BROMO-4-METHYL-PYRIDIN-2-YL)-ACETAMIDE - Introduction

2-Acetamido-5-bromo-4-methylpyridine is an organic compound with the chemical formula C10H12BrNO. Here is some basic information about it:

Nature:
-Appearance: light yellow to yellow crystal or powder
-Solubility: Soluble in ethanol, chloroform and dimethyl sulfoxide, insoluble in water
-Melting point: approx. 110-113°C

Use:
-2-acetamido-5-bromo-4-methylpyridine is a commonly used organic synthesis intermediate. It can be used to synthesize various drugs and pesticides, and has a wide range of applications.
-It is also used as a reaction catalyst and reducing agent, and plays an important role in some chemical reactions.

Preparation Method:
-2-acetamido-5-bromo-4-methylpyridine can be synthesized by the following steps:
1. Add methanol and potassium carbonate to bromobenzene, and stir and mix.
2. Acetamide was slowly added at -5 to 0°C.
3. The reaction mixture was further stirred at the reaction temperature for 1-2 hours.
4. The product of 2-acetamido-5-bromo-4-methylpyridine was obtained by filtration and crystallization.

Safety Information:
-2-acetamido-5-bromo-4-methylpyridine should take appropriate protective measures during use, such as wearing gloves, protective glasses and protective clothing.
-Avoid inhaling the dust or vapor of the compound, and avoid direct contact with skin and eyes.
-During use, please ensure good ventilation conditions and pay attention to the danger of fire and static electricity.
-If ingested or inhaled, seek medical attention immediately and bring the compound's safety data sheet to a medical facility.

Last Update：2024-04-09 02:00:42