N-(5-bromo-2-hydroxybenzoyl)glycine
N-(5-bromo-2-hydroxybenzoyl)glycine
CAS: 69507-30-8
Molecular Formula: C9H8BrNO4
N-(5-bromo-2-hydroxybenzoyl)glycine - Names and Identifiers
| Name | N-(5-bromo-2-hydroxybenzoyl)glycine |
| Synonyms | 5-BROMO-2-HYDROXYHIPPURIC ACID 97 N-(5-bromo-2-hydroxybenzoyl)glycine Glycine, N-(5-bromo-2-hydroxybenzoyl)- |
| CAS | 69507-30-8 |
| InChI | InChI=1/C9H8BrNO4/c10-5-1-2-7(12)6(3-5)9(15)11-4-8(13)14/h1-3,12H,4H2,(H,11,15)(H,13,14) |
N-(5-bromo-2-hydroxybenzoyl)glycine - Physico-chemical Properties
| Molecular Formula | C9H8BrNO4 |
| Molar Mass | 274.07 |
| Density | 1.762±0.06 g/cm3(Predicted) |
| Melting Point | 211-215°C(lit.) |
| Boling Point | 476.4±45.0 °C(Predicted) |
| Flash Point | 241.9°C |
| Vapor Presure | 6.96E-10mmHg at 25°C |
| pKa | 3.66±0.10(Predicted) |
| Refractive Index | 1.634 |
N-(5-bromo-2-hydroxybenzoyl)glycine - Risk and Safety
| WGK Germany | 3 |
N-(5-bromo-2-hydroxybenzoyl)glycine - Introduction
N-glycine is an organic compound with the chemical formula C9H8BrNO4. It is a white to yellow crystal or crystalline powder. The following is an introduction to the nature, use, preparation and safety information of N-(glycine):
Nature:
-Appearance: White to yellow crystal or crystalline powder.
-Melting point: about 205-208 degrees Celsius.
-Solubility: Soluble in hot water and organic solvents such as alcohols and ethers.
Use:
-Pharmaceutical field: N-(glycine) as a drug raw material, is used for the synthesis of some medicines, such as non-steroidal anti-inflammatory drugs and anti-tumor drugs.
-Chemical research: It can also be used as an important intermediate in organic chemical synthesis.
Preparation Method:
The preparation of N-(a) glycine can usually be completed by the following steps:
1. the reaction of p-hydroxybenzoic acid and hydrobromic acid to generate p-bromobenzoic acid.
2. p-bromobenzoic acid and glycine are reacted to obtain N-(phenyl) glycine.
Safety Information:
-Due to the specific use and environmental conditions of each chemical, the product quality certificate and safety instructions should be read carefully before use, and the corresponding safety operation procedures should be followed.
- N-glycine is a chemical that may have adverse effects on human health. Wear appropriate personal protective equipment such as gloves and goggles during operation to avoid contact with skin and eyes.
-When encountering a fire source, toxic gas or harmful smoke may be produced. Therefore, contact with strong oxidants and high temperature substances should be avoided during use.
Please note that the above information is for reference only. When using chemicals, it is important to follow correct operating methods and safety measures.
Nature:
-Appearance: White to yellow crystal or crystalline powder.
-Melting point: about 205-208 degrees Celsius.
-Solubility: Soluble in hot water and organic solvents such as alcohols and ethers.
Use:
-Pharmaceutical field: N-(glycine) as a drug raw material, is used for the synthesis of some medicines, such as non-steroidal anti-inflammatory drugs and anti-tumor drugs.
-Chemical research: It can also be used as an important intermediate in organic chemical synthesis.
Preparation Method:
The preparation of N-(a) glycine can usually be completed by the following steps:
1. the reaction of p-hydroxybenzoic acid and hydrobromic acid to generate p-bromobenzoic acid.
2. p-bromobenzoic acid and glycine are reacted to obtain N-(phenyl) glycine.
Safety Information:
-Due to the specific use and environmental conditions of each chemical, the product quality certificate and safety instructions should be read carefully before use, and the corresponding safety operation procedures should be followed.
- N-glycine is a chemical that may have adverse effects on human health. Wear appropriate personal protective equipment such as gloves and goggles during operation to avoid contact with skin and eyes.
-When encountering a fire source, toxic gas or harmful smoke may be produced. Therefore, contact with strong oxidants and high temperature substances should be avoided during use.
Please note that the above information is for reference only. When using chemicals, it is important to follow correct operating methods and safety measures.
Last Update：2024-04-09 21:04:16
