N-(9-Fluorenylmethoxycarbonyl)-3-(4-thiazoyl)-D-alanine
Fmoc-3-(4-Thiazolyl)-D-alanine
CAS: 205528-33-2
Molecular Formula: C21H18N2O4S
N-(9-Fluorenylmethoxycarbonyl)-3-(4-thiazoyl)-D-alanine - Names and Identifiers
| Name | Fmoc-3-(4-Thiazolyl)-D-alanine |
| Synonyms | RARECHEM BK PT 0202 FMOC-D-4-THIAZOLYALANINE Fmoc-D-4-Thiazoylalanine Fmoc-D-4-Thiazolylalanine FMOC-D-4-THIAZOLYLALANINE (R)-N-FMOC-4-Thiazoylalanine (R)-N-FMOC-4-THIAZOYLALANINE Fmoc-3-(4-Thiazolyl)-D-alanine N-(9-Fluorenylmethoxycarbonyl)-3-(4-thiazoyl)-D-alanine (R)-N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-3-(4-THIAZOLYL)-ALANINE (2R)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-(4-thiazolyl)propanoate (R)-N-FMOC-4-ThiazoylalanineN-(9-Fluorenylmethoxycarbonyl)-4-thiazoyl-D-alanine |
| CAS | 205528-33-2 |
| InChI | InChI=1/C21H18N2O4S/c24-20(25)19(9-13-11-28-12-22-13)23-21(26)27-10-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,11-12,18-19H,9-10H2,(H,23,26)(H,24,25)/p-1/t19-/m1/s1 |
N-(9-Fluorenylmethoxycarbonyl)-3-(4-thiazoyl)-D-alanine - Physico-chemical Properties
| Molecular Formula | C21H18N2O4S |
| Molar Mass | 394.44 |
| Density | 1.2468 (rough estimate) |
| Melting Point | 180.2 °C |
| Boling Point | 647.5±55.0 °C(Predicted) |
| Flash Point | 345.4°C |
| Vapor Presure | 1.19E-17mmHg at 25°C |
| pKa | 3.42±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.6930 (estimate) |
N-(9-Fluorenylmethoxycarbonyl)-3-(4-thiazoyl)-D-alanine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
N-(9-Fluorenylmethoxycarbonyl)-3-(4-thiazoyl)-D-alanine - Introduction
Fmoc-3-(4-Thiazolyl)-D-alanine is an amino acid molecule containing a protecting group with the following properties:
1. Appearance and solubility: Fmoc-3-(4-Thiazolyl)-D-alanine is a white crystalline solid, soluble in some organic solvents, such as dichloromethane, methanol, etc.
2. Chiral properties: Fmoc-3-(4-Thiazolyl)-D-alanine are compounds with chiral centers, which can exist in D-or L-configuration, Fmoc-3-(4-Thiazolyl)-D-alanine selectively use the D-configuration.
Fmoc-3-(4-Thiazolyl)-D-alanine main uses are as follows:
1. Biological activity Research: As an amino acid protecting group, Fmoc-3-(4-Thiazolyl)-D-alanine is often used in the synthesis of peptides and protein molecules to study their biological activities and interactions.
2. Drug research and development: Fmoc-3-(4-Thiazolyl)-D-alanine is also used in drug research and development, and can be used to synthesize antibiotics, anticancer drugs, etc.
The preparation of Fmoc-3-(4-Thiazolyl)-D-alanine is generally divided into two steps:
1. First, thiazolyl propionic acid is reacted with DMAP (dimethylaminopyridine) in dichloromethane to generate thiazolyl propionyl chloride.
2. Then, thiazolyl propionyl chloride is reacted with Fmoc-D-alanine under basic conditions to generate Fmoc-3-(4-Thiazolyl)-D-alanine.
Regarding safety information, Fmoc-3-(4-Thiazolyl)-D-alanine are generally organic compounds and have certain potential hazards. When using the need to pay attention to the following points:
1. Avoid inhalation: good ventilation measures should be taken to avoid inhalation of dust or vapor.
2. Avoid contact with skin and eyes: During use, avoid direct contact with Fmoc-3-(4-Thiazolyl)-D-alanine to avoid irritation or damage to skin and eyes.
3. Storage and handling: Fmoc-3-(4-Thiazolyl)-D-alanine should be stored in a dry, cool place, away from fire and oxidant. Disposal of waste shall comply with relevant environmental regulations.
When using and handling Fmoc-3-(4-Thiazolyl)-D-alanine, users should follow the laboratory's safety practices and take personal protective measures to ensure safety.
1. Appearance and solubility: Fmoc-3-(4-Thiazolyl)-D-alanine is a white crystalline solid, soluble in some organic solvents, such as dichloromethane, methanol, etc.
2. Chiral properties: Fmoc-3-(4-Thiazolyl)-D-alanine are compounds with chiral centers, which can exist in D-or L-configuration, Fmoc-3-(4-Thiazolyl)-D-alanine selectively use the D-configuration.
Fmoc-3-(4-Thiazolyl)-D-alanine main uses are as follows:
1. Biological activity Research: As an amino acid protecting group, Fmoc-3-(4-Thiazolyl)-D-alanine is often used in the synthesis of peptides and protein molecules to study their biological activities and interactions.
2. Drug research and development: Fmoc-3-(4-Thiazolyl)-D-alanine is also used in drug research and development, and can be used to synthesize antibiotics, anticancer drugs, etc.
The preparation of Fmoc-3-(4-Thiazolyl)-D-alanine is generally divided into two steps:
1. First, thiazolyl propionic acid is reacted with DMAP (dimethylaminopyridine) in dichloromethane to generate thiazolyl propionyl chloride.
2. Then, thiazolyl propionyl chloride is reacted with Fmoc-D-alanine under basic conditions to generate Fmoc-3-(4-Thiazolyl)-D-alanine.
Regarding safety information, Fmoc-3-(4-Thiazolyl)-D-alanine are generally organic compounds and have certain potential hazards. When using the need to pay attention to the following points:
1. Avoid inhalation: good ventilation measures should be taken to avoid inhalation of dust or vapor.
2. Avoid contact with skin and eyes: During use, avoid direct contact with Fmoc-3-(4-Thiazolyl)-D-alanine to avoid irritation or damage to skin and eyes.
3. Storage and handling: Fmoc-3-(4-Thiazolyl)-D-alanine should be stored in a dry, cool place, away from fire and oxidant. Disposal of waste shall comply with relevant environmental regulations.
When using and handling Fmoc-3-(4-Thiazolyl)-D-alanine, users should follow the laboratory's safety practices and take personal protective measures to ensure safety.
Last Update：2024-04-09 21:01:54
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Product Name: FMOC-D-4-THIAZOLYLALANINE Visit Supplier Webpage Request for quotation
CAS: 205528-33-2
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Mobile: 18021002903
QQ: 3008007409
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CAS: 205528-33-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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