N-(N-BETA-BOC-AMINOETHYL)-GLY-OET

N-(N-BETA-BOC-AMINOETHYL)-GLY-OET - Names and Identifiers

Name	N-(N-.beta.-Boc-aminoethyl)-Gly-OEt
Synonyms	PNA BUILDING BLOCK N-(N-BETA-BOC-AMINOETHYL)-GLYCINE N-(N-BETA-BOC-AMINOETHYL)-GLY-OET N-(N-.beta.-Boc-aminoethyl)-Gly-OEt ETHYL N-[(2-BOC-AMINO)ETHYL]GLYCINATE HYDROCHLORIDE Ethyl [2-(Boc-Amino)Ethylamino]Acetate Hydrochloride ETHYL [2-(BOC-AMINO)ETHYLAMINO]ACETATE HYDROCHLORIDE N-[2-(BOC-AMINO)ETHYL]GLYCINE ETHYL ESTER HYDROCHLORIDE N-[2-(tert-Butoxycarbonylamino)ethyl]glycine Ethyl Ester
CAS	72648-80-7

N-(N-BETA-BOC-AMINOETHYL)-GLY-OET - Physico-chemical Properties

Molecular Formula	C11H22N2O4
Molar Mass	246.3
Density	1.049±0.06 g/cm3(Predicted)
Melting Point	116-119°C
Boling Point	352.0±27.0 °C(Predicted)
Appearance	clear liquid
Color	Colorless to Yellow
pKa	12.50±0.46(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.4520-1.4560

N-(N-BETA-BOC-AMINOETHYL)-GLY-OET - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	10-21

N-(N-BETA-BOC-AMINOETHYL)-GLY-OET - Introduction

N-(N-.beta.-Boc-aminoethyl)-Gly-OEt (N-(N-. Boc-aminoethyl.-Gly-OEt)) is a compound with the following properties and uses:

Nature:
-Appearance: Colorless or white solid
-Molecular formula: C14H27N3O4
-Solubility: Soluble in organic solvents such as chloroform, dimethylformamide and ethanol, low solubility in water
-Storage conditions: Store in a dry, cool place, avoid light and humidity

Use:
- N-(N-.beta.-Boc-aminoethyl)-Gly-OEt are mainly used as intermediates in organic synthesis. It is commonly used in the synthesis of amino acids with protecting groups, as well as in the synthesis of peptides and proteins.

Preparation Method:
N-(N-.beta.-Boc-aminoethyl)-Gly-OEt were prepared as follows:
1. Condensation of glycine with tert-butyl hydroxymethyl carbonate and reaction under alkaline conditions to generate N-tert-butyl hydroxymethyl glycine.
2. Reaction of N-tert-butylhydroxymethylglycine with ethanol to produce N-[2-(tert-butoxycarbonylamino) ethyl] glycine ethyl ester.
3. Finally, the resulting product is reacted with hydrochloric acid to form N-(N-.beta.-Boc-aminoethyl)-Gly-OEt.

Safety Information:
- N-(N-.beta.-Boc-aminoethyl)-Gly-OEt need to operate under laboratory conditions, pay attention to personal protective measures, such as wearing gloves, glasses and lab clothes.
-Avoid direct contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Avoid contact with water or humid air during operation or storage.
-Pay attention to the accumulation of fire source and static electricity during the preparation process to ensure the safety of the operating environment.
-Detailed safety information should refer to the safety data sheet (MSDS) provided by the chemical supplier.

Last Update：2024-04-10 22:29:15