Name | N-(P-SULFAMOYLPHENETHYL)ACETAMIDE |
Synonyms | Glipizide Impurity 16 N-(P-SULFAMOYLPHENETHYL)ACETAMIDE N-[2-(4-sulfamoylphenyl)ethyl]acetamide 4-(2-acetylaminoethyl)benzenesulfonamide N-[2-(4-Sulphamoylphenyl)ethyl]acetamide 2-(4-sulfamoylphenyl)ethanaminium chloride N-ACETYL (2-AMINOETHYL)BENZENE SULPHONAMIDE N-ACETYL-4-(2-AMINOETHYL)-BENZENESULFONAMIDE 4-[2-(N-Acetylamino)-ethyl]-benzenesulfonamide 4-[2-(N-Acetyl amino)ethyl]benzene sulfonamide N-[2-[4-(aminosulphonyl)phenyl]ethyl]acetamide |
CAS | 41472-49-5 |
EINECS | 255-386-5 |
InChI | InChI=1/C8H12N2O2S.ClH/c9-6-5-7-1-3-8(4-2-7)13(10,11)12;/h1-4H,5-6,9H2,(H2,10,11,12);1H |
Molecular Formula | C10H14N2O3S |
Molar Mass | 242.29 |
Density | 1.274±0.06 g/cm3(Predicted) |
Melting Point | 168-174°C |
Boling Point | 387.4°C at 760 mmHg |
Flash Point | 188.1°C |
Vapor Presure | 3.31E-06mmHg at 25°C |
pKa | 10.16±0.10(Predicted) |
Storage Condition | 2-8°C |
Physical and Chemical Properties | White or colorless powder crystals. |
Use | It is an important intermediate in the synthesis of sulfonylurea glibenclamide (glyburide,glibenclamide, glyburide) and glipizide (glipizide, for the treatment of type 2 diabetes. It is also used as a dye intermediate. |
Use | is an important intermediate for the synthesis of sulfonylurea drugs glibenclamide (glyburide,glibenclamide, glibenclamide) and glipizide (glipizide, pyridoxine). These two drugs are a new generation of sulfonylurea drugs used to treat type 2 diabetes. Also used as a dye intermediate. |