N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE

N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE - Names and Identifiers

Name	N-BOC-Toluenesulfonamide
Synonyms	LABOTEST-BB LT00453242 N-BOC-Toluenesulfonamide N-BOC-P-TOLUENESULFONAMIDE (tert-Butoxycarbonyl)tosylamine Tosylcarbamic acid tert-butyl ester N-Tosylcarbamic acid tert-butyl ester N-(tert-Butoxycarbonyl-p-tolunesulfonamide N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE N-(p-Tolylsulfonyl)carbamic acid tert-butyl ester
CAS	18303-04-3
InChIKey	DUTLOVSBVBGNDM-UHFFFAOYSA-N

N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE - Physico-chemical Properties

Molecular Formula	C12H17NO4S
Molar Mass	271.33
Density	1.201±0.06 g/cm3(Predicted)
Melting Point	121-123°C(lit.)
Solubility	chloroform: soluble25mg/mL, clear, colorless
Appearance	powder to crystal
Color	White to Almost white
pKa	4.84±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
MDL	MFCD00134267

N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29350090

N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE - Introduction

N-BOC-Toluenesulfonamide(N-BOC-Toluenesulfonamide) is an organic compound whose molecular formula is C14H21NO4S.

Nature:
N-BOC-Toluenesulfonamide is a white crystalline solid with high thermal stability. It is stable at room temperature, has low solubility, and has low solubility in common organic solvents. Its melting point is about 113-119 degrees Celsius.

Use:
N-BOC-Toluenesulfonamide is a common reagent in organic synthesis. It can be used as a protecting group to protect amino acids or other amino-containing compounds to prevent other reactions from occurring at the amino group. The protecting group can be removed as soon as necessary by appropriate reaction conditions.

Preparation Method:
The preparation method of N-BOC-Toluenesulfonamide is generally obtained by reacting p-toluenesulfonamide with tert-butyl hydroxyformate under alkaline conditions. The reaction process is usually carried out at low temperature, mainly to avoid the occurrence of side reactions.

Safety Information:
The N-BOC-Toluenesulfonamide should be less dangerous under normal conditions of use. However, it is still a chemical and care should be taken for proper use and storage. Avoid contact with strong oxidants, avoid inhalation or skin contact. When used in a laboratory or industrial environment, the appropriate safe operating procedures should be followed.

Last Update：2024-04-10 22:29:15