N-(m-Tolyl)piperazine
1-(3-Methylphenyl)-piperazine
CAS: 41186-03-2
Molecular Formula: C11H16N2
N-(m-Tolyl)piperazine - Names and Identifiers
| Name | 1-(3-Methylphenyl)-piperazine |
| Synonyms | RARECHEM AH CK 0136 N-(m-Tolyl)piperazine 1-(M-TOLYL)PIPERAZINE LABOTEST-BB LT00233106 1-(3-METHYLPHENYL)PIPERAZINE 1-(3-Methylphenyl)piperazine 1-(3-Methylphenyl)-piperazine Piperazine, 1-(3-methylphenyl)- (9CI) 1-(M-TOLYL)PIPERAZINE [1-(3-METHYLPHENYL)-PIPERAZINE] |
| CAS | 41186-03-2 |
| EINECS | 255-251-0 |
| InChI | InChI=1/C11H16N2/c1-10-3-2-4-11(9-10)13-7-5-12-6-8-13/h2-4,9,12H,5-8H2,1H3 |
N-(m-Tolyl)piperazine - Physico-chemical Properties
| Molecular Formula | C11H16N2 |
| Molar Mass | 176.26 |
| Density | 1.04 |
| Melting Point | 125-128 °C |
| Boling Point | 112 °C |
| Flash Point | 154°C |
| Vapor Presure | 0.000299mmHg at 25°C |
| Appearance | Morphological Viscous Liquid |
| Color | Clear colorless to yellow |
| pKa | 9.05±0.10(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.5755-1.5785 |
N-(m-Tolyl)piperazine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN 3267 8/PG III |
| HS Code | 29335990 |
| Hazard Class | IRRITANT |
| Packing Group | III |
N-(m-Tolyl)piperazine - Upstream Downstream Industry
N-(m-Tolyl)piperazine - Introduction
1-(3-Methylphenyl)-piperazine is an organic compound with the chemical formula C11H16N2. It is a white crystalline solid, soluble in ethanol and chloroform, insoluble in water.
1-(3-Methylphenyl)-piperazine is commonly used as a pharmaceutical compound and has various applications in the pharmaceutical field. It is used as an intermediate for antipsychotic drugs, such as clozapine, etc. In addition, it can be used as a hypnotic and sedative. Because of its effect on the central nervous system, it has some value in medicine and neurological research.
The method for preparing 1-(3-Methylphenyl)-piperazine is usually to react piperazine with 3-methylphenol under alkaline conditions. First, piperazine is reacted with a base to form the corresponding salt, which is then reacted with 3-methylphenol to give 1-(3-Methylphenyl)-piperazine. The preparation process requires attention to nitrogen protection and the use of efficient stirring to ensure the progress of the reaction and the purity of the product.
Regarding safety, 1-(3-Methylphenyl)-piperazine is relatively safe under normal conditions of use. However, as an organic compound, it should be stored in a dry, cool, well-ventilated place, away from combustibles and oxidants. Wear appropriate protective equipment such as gloves and goggles during handling, handling and storage. During use, direct contact with the skin and inhalation of its vapors should be avoided. In case of accidental contact or inhalation, wash the skin immediately or go to a ventilated place.
1-(3-Methylphenyl)-piperazine is commonly used as a pharmaceutical compound and has various applications in the pharmaceutical field. It is used as an intermediate for antipsychotic drugs, such as clozapine, etc. In addition, it can be used as a hypnotic and sedative. Because of its effect on the central nervous system, it has some value in medicine and neurological research.
The method for preparing 1-(3-Methylphenyl)-piperazine is usually to react piperazine with 3-methylphenol under alkaline conditions. First, piperazine is reacted with a base to form the corresponding salt, which is then reacted with 3-methylphenol to give 1-(3-Methylphenyl)-piperazine. The preparation process requires attention to nitrogen protection and the use of efficient stirring to ensure the progress of the reaction and the purity of the product.
Regarding safety, 1-(3-Methylphenyl)-piperazine is relatively safe under normal conditions of use. However, as an organic compound, it should be stored in a dry, cool, well-ventilated place, away from combustibles and oxidants. Wear appropriate protective equipment such as gloves and goggles during handling, handling and storage. During use, direct contact with the skin and inhalation of its vapors should be avoided. In case of accidental contact or inhalation, wash the skin immediately or go to a ventilated place.
Last Update：2024-04-09 21:51:49
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Spot supply
Product Name: Centhaquin Impurity 2 Visit Supplier Webpage Request for quotationCAS: 41186-03-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 1-(3-Methylphenyl)Piperazine Visit Supplier Webpage Request for quotation
CAS: 41186-03-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 41186-03-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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Raw Materials for N-(m-Tolyl)piperazine