N-(tert-Butoxycarbonyl)-3-phenyl-D-phenylalaninol

N-(tert-Butoxycarbonyl)-3-phenyl-D-phenylalaninol - Names and Identifiers

Name	N-(tert-butoxycarbonyl)-beta-phenyl-D-phenylalaninol
Synonyms	Zinc02389290 N-Boc-beta-Phenyl-D-Phenylalaninol N-BOC-BETA-PHENYL-D-PHENYLALANINOL N-(TERT-BUTOXYCARBONYL)-BETA-PHENYL-D-PH n-(tert-butoxycarbonyl)-β-phenyl-d-phenylalaninol N-(tert-Butoxycarbonyl)-3-phenyl-D-phenylalaninol N-(TERT-BUTOXYCARBONYL)-BETA-PHENYL-D-PHENYLALANINOL N-(tert-butoxycarbonyl)-beta-phenyl-D-phenylalaninol tert-butyl [(2R)-3-hydroxy-1,1-diphenylpropan-2-yl]carbamate tert-butyl N-[(2R)-3-hydroxy-1,1-diphenylpropan-2-yl]carbamate N-[1-hydroxy-3-(3-phenylphenyl)propan-2-yl]carbamic acid tert-butyl ester
CAS	155836-48-9
EINECS	604-604-1
InChI	InChI=1/C20H25NO3/c1-20(2,3)24-19(23)21-18(14-22)13-15-8-7-11-17(12-15)16-9-5-4-6-10-16/h4-12,18,22H,13-14H2,1-3H3,(H,21,23)/t18-/m1/s1

N-(tert-Butoxycarbonyl)-3-phenyl-D-phenylalaninol - Physico-chemical Properties

Molecular Formula	C20H25NO3
Molar Mass	327.42
Melting Point	114-116°C(lit.)
Specific Rotation(α)	-21 º (c=1 in methanol)
Storage Condition	2-8°C
Refractive Index	1.553

N-(tert-Butoxycarbonyl)-3-phenyl-D-phenylalaninol - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

N-(tert-Butoxycarbonyl)-3-phenyl-D-phenylalaninol - Introduction

N-(tert-butoxycarbonyl)-beta-phenyl-D-phenylalaninol, also known as N-tert-butoxycarbonyl-3-phenyl-D-phenylalaninol, is an organic compound. Its nature is as follows:

1. Appearance: White crystalline solid.
2. Molecular formula: C23H29NO3.
3. Molecular weight: 367.48g/mol.
4. Melting Point: about 95-98 ℃.
5. Good solubility in organic solvents.
6. Belong to stereoisomer.

N-(tert-butoxycarbonyl)-beta-phenyl-D-phenylalaninol have the following uses:

1. Drug synthesis: as an intermediate in organic synthesis, it can be used to prepare organic compounds with biological activity.
2. Pharmaceutical field: It has the potential to inhibit the growth of tumor cells and can be used for cancer treatment research.
3. Cosmetics field: used as anti-aging and whitening agent ingredients.

The method of preparing N-(tert-butoxycarbonyl)-beta-phenyl-D-phenylalaninol generally includes the following steps:

1. The hydroxyl group of phenyl-D-phenylalanine is protected as a tert-butoxycarbonyl group.
2. In an appropriate solvent, it reacts with an electrophilic reagent (such as iodinated sulfoxide) to generate an electrophilic iodine intermediate.
3. The electrophilic iodine intermediate reacts with phenyl-D-phenylalanine ethyl ester to generate the target product.

When using and handling N-(tert-butoxycarbonyl)-beta-phenyl-D-phenylalaninol, you need to pay attention to safety precautions:

1. The compound may cause irritation and sensitivity to the eyes, skin and respiratory tract. Wear appropriate protective equipment, such as gloves and goggles.
2. During the operation, avoid inhaling the dust or vapor of the solution to avoid discomfort.
3. Storage, need to keep dry, avoid contact with oxygen, high temperature and fire.
4. When using or handling the compound, follow laboratory safety practices and properly dispose of waste. In the event of an accident, appropriate emergency measures shall be taken immediately.

Please note that the use and handling of chemicals should be carried out under the guidance of professionals and in accordance with relevant safety measures and regulatory requirements.

Last Update：2024-04-09 21:21:28