N-(tert-Butyloxycarbonyl)-N-methyl-D-leucine
Boc-N-methyl-D-leucine
CAS: 89536-84-5
Molecular Formula: C12H23NO4
N-(tert-Butyloxycarbonyl)-N-methyl-D-leucine - Names and Identifiers
| Name | Boc-N-methyl-D-leucine |
| Synonyms | Boc-N-Me-D-Leu-OH BOC-BETA-TBU-D-ALA-OH BOC-T-BUTYL-D-ALANINE Boc-N-methyl-D-leucine BOC-BETA-TBU-D-ALANINE N-(tert-butoxycarbonyl)-N-methyl-D-leucine N-ALPHA-T-BUTOXYCARBONYL-D-T-BUTYL-ALANINE N-(tert-Butyloxycarbonyl)-N-methyl-D-leucine N-(tert-Butyloxycarbonyl)-N-methyl-D-leucine N-ALPHA-T-BUTOXYCARBONYL-D-GAMMA-METHYL-LEUCINE |
| CAS | 89536-84-5 |
| InChI | InChI=1/C12H23NO4/c1-8(2)7-9(10(14)15)13(6)11(16)17-12(3,4)5/h8-9H,7H2,1-6H3,(H,14,15)/t9-/m1/s1 |
N-(tert-Butyloxycarbonyl)-N-methyl-D-leucine - Physico-chemical Properties
| Molecular Formula | C12H23NO4 |
| Molar Mass | 245.32 |
| Density | 1.053g/cm3 |
| Melting Point | 64-65°C |
| Boling Point | 338.2°C at 760 mmHg |
| Flash Point | 158.3°C |
| Vapor Presure | 1.86E-05mmHg at 25°C |
| BRN | 4184551 |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.466 |
N-(tert-Butyloxycarbonyl)-N-methyl-D-leucine - Risk and Safety
| WGK Germany | 3 |
N-(tert-Butyloxycarbonyl)-N-methyl-D-leucine - Introduction
Boc-N-methyl-D-leucine(Boc-N-methyl-D-leucine) is an organic compound whose chemical formula is C15H29NO4. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Boc-N-methyl-D-leucine is a white crystalline powder.
-Solubility: Soluble in general organic solvents (such as dimethyl sulfoxide, methanol, dimethylformamide).
Use:
- Boc-N-methyl-D-leucine is commonly used in the synthesis of amino acid derivatives in peptides or protein drugs, and plays an important role in peptide chemistry and protein engineering.
-It can be used as a protecting group in organic synthesis to protect the amine group of D-leucine.
Preparation Method:
- Boc-N-methyl-D-leucine can be prepared by reacting N-methyl-D-leucine with tert-butoxycarbonyl chloride (BOC-Cl).
-This reaction is carried out in an organic solvent such as dimethylformamide, and the yield and purity are controlled by controlling the temperature and reaction time.
Safety Information:
- Boc-N-methyl-D-leucine has no apparent toxicity, but care must be taken to prevent inhalation, skin contact and ingestion.
-Wear lab gloves, goggles, and lab coats when using and handling the compound to avoid contact with skin and eyes.
-When storing and handling this compound, keep it in a cool, dry, well-ventilated place, away from fire and oxidizing agents.
Nature:
-Appearance: Boc-N-methyl-D-leucine is a white crystalline powder.
-Solubility: Soluble in general organic solvents (such as dimethyl sulfoxide, methanol, dimethylformamide).
Use:
- Boc-N-methyl-D-leucine is commonly used in the synthesis of amino acid derivatives in peptides or protein drugs, and plays an important role in peptide chemistry and protein engineering.
-It can be used as a protecting group in organic synthesis to protect the amine group of D-leucine.
Preparation Method:
- Boc-N-methyl-D-leucine can be prepared by reacting N-methyl-D-leucine with tert-butoxycarbonyl chloride (BOC-Cl).
-This reaction is carried out in an organic solvent such as dimethylformamide, and the yield and purity are controlled by controlling the temperature and reaction time.
Safety Information:
- Boc-N-methyl-D-leucine has no apparent toxicity, but care must be taken to prevent inhalation, skin contact and ingestion.
-Wear lab gloves, goggles, and lab coats when using and handling the compound to avoid contact with skin and eyes.
-When storing and handling this compound, keep it in a cool, dry, well-ventilated place, away from fire and oxidizing agents.
Last Update：2024-04-09 02:00:49
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