N-(tert-butoxycarbonyl)-3-(3-pyridyl)-L-alanine
Boc-3-(3-pyridyl)-L-alanine
CAS: 117142-26-4
Molecular Formula: C13H18N2O4
N-(tert-butoxycarbonyl)-3-(3-pyridyl)-L-alanine - Names and Identifiers
| Name | Boc-3-(3-pyridyl)-L-alanine |
| Synonyms | Boc-3-Pal-OH Boc-L-3-Pyridylalanine Boc-3-(3-Pyridyl)-Alanine Boc-L-3-(3-Pyridyl)-alanine Boc-3-(3-pyridyl)-L-alanine Boc-3-Pal-OH ] Boc-3-(3-pyridyl)-L-alanine N-(tert-butoxycarbonyl)-3-(3-pyridyl)-L-alanine Boc-β-(3-pyridyl)-Ala-OH, Boc-3-(3-pyridyl)-L-alanine 3-Pyridinepropanoicacid, a-[[(1,1-diMethylethoxy)carbonyl]aMino] (2S)-2-{[(tert-butoxy)carbonyl]aMino}-3-(pyridin-3-yl)propanoic acid |
| CAS | 117142-26-4 |
| InChI | InChI=1/C13H18N2O4/c1-13(2,3)19-12(18)15-10(11(16)17)7-9-5-4-6-14-8-9/h4-6,8,10H,7H2,1-3H3,(H,15,18)(H,16,17)/t10-/m0/s1 |
N-(tert-butoxycarbonyl)-3-(3-pyridyl)-L-alanine - Physico-chemical Properties
| Molecular Formula | C13H18N2O4 |
| Molar Mass | 266.3 |
| Density | 1.1738 (rough estimate) |
| Melting Point | 136-142°C |
| Boling Point | 409.5°C (rough estimate) |
| Specific Rotation(α) | 15.5 º (c=1% in EtOH) |
| Flash Point | 227.7°C |
| Vapor Presure | 5.43E-09mmHg at 25°C |
| Appearance | Solid |
| Color | Off-white to pale yellow |
| BRN | 7625087 |
| pKa | 3.43±0.10(Predicted) |
| Storage Condition | −20°C |
| Refractive Index | 1.6450 (estimate) |
| MDL | MFCD00079681 |
| Physical and Chemical Properties | Storage Conditions:? 20℃ WGK Germany:3 |
N-(tert-butoxycarbonyl)-3-(3-pyridyl)-L-alanine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
N-(tert-butoxycarbonyl)-3-(3-pyridyl)-L-alanine - Introduction
N-tert-Butoxycarbonyl-3-pyridyl-L-alanine is an organic compound with the following properties:
1. appearance: white crystalline powder solid.
2. solubility: soluble in water and common organic solvents.
3. Thermal stability: relatively stable at room temperature, but decomposition may occur at high temperature.
4. optical properties: with optical activity, can rotate the polarization angle of plane polarized light.
The main use of N-tert-butoxycarbonyl-3-pyridyl-L-alanine is as a raw material and intermediate in chemical synthesis. It can be used for the synthesis of peptides, protein drugs and other organic compounds. Due to its optical properties, it can also be used as a derivative of a chiral catalyst.
The preparation method of the compound generally adopts the method of chemical synthesis. The specific steps include reacting tert-butanol and pyridine to obtain a synthetic intermediate tert-butoxycarbonyl pyridine, which is then reacted with L-alanine to form N-tert-butoxycarbonyl-3-pyridyl-L-alanine.
Regarding safety information, the specific toxicity and danger of N-tert-butoxycarbonyl-3-pyridyl-L-alanine have not been clearly reported. However, as a chemical, it still needs to be handled and stored under appropriate laboratory conditions, and strictly follow relevant safe operating procedures. When in use, it is recommended to wear personal protective equipment, such as laboratory gloves, goggles and laboratory coats, and ensure that the operating area is well ventilated. If necessary, refer to the relevant Safety Data Sheet (SDS) for more detailed information.
1. appearance: white crystalline powder solid.
2. solubility: soluble in water and common organic solvents.
3. Thermal stability: relatively stable at room temperature, but decomposition may occur at high temperature.
4. optical properties: with optical activity, can rotate the polarization angle of plane polarized light.
The main use of N-tert-butoxycarbonyl-3-pyridyl-L-alanine is as a raw material and intermediate in chemical synthesis. It can be used for the synthesis of peptides, protein drugs and other organic compounds. Due to its optical properties, it can also be used as a derivative of a chiral catalyst.
The preparation method of the compound generally adopts the method of chemical synthesis. The specific steps include reacting tert-butanol and pyridine to obtain a synthetic intermediate tert-butoxycarbonyl pyridine, which is then reacted with L-alanine to form N-tert-butoxycarbonyl-3-pyridyl-L-alanine.
Regarding safety information, the specific toxicity and danger of N-tert-butoxycarbonyl-3-pyridyl-L-alanine have not been clearly reported. However, as a chemical, it still needs to be handled and stored under appropriate laboratory conditions, and strictly follow relevant safe operating procedures. When in use, it is recommended to wear personal protective equipment, such as laboratory gloves, goggles and laboratory coats, and ensure that the operating area is well ventilated. If necessary, refer to the relevant Safety Data Sheet (SDS) for more detailed information.
Last Update：2024-04-09 21:54:55
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Spot supply
Product Name: Boc-3-(3-Pyridyl)-Alanine Visit Supplier Webpage Request for quotationCAS: 117142-26-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: Boc-3-pal-OH Request for quotationCAS: 117142-26-4
Tel: 86-10-10086 81625225
Email: yeqim@boyechemicals.com
Mobile: 86-15387090420
QQ: 1377812380
Wechat: 15387090420
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