N-(tert-butoxycarbonyl)-D-prolinal
N-(tert-butoxycarbonyl)-D-prolinal
CAS: 73365-02-3
Molecular Formula: C10H17NO3
N-(tert-butoxycarbonyl)-D-prolinal - Names and Identifiers
| Name | N-(tert-butoxycarbonyl)-D-prolinal |
| Synonyms | BOC-D-PROLINAL N-T-BOC-D-PROLINAL N-t-BOC-D-prolinal (R)-N-BOC-PROLINAL N-(tert-butoxycarbonyl)-D-prolinal N-(TERT-BUTOXYCARBONYL)-D-PROLINAL (R)-(+)-1-BOC-2-PYRROLIDINECARBALDEHYDE tert-butyl 2-formylpyrrolidine-1-carboxylate (R)-2-FORMYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-2-FORMYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-N-BOC-PROLINAL |
| CAS | 73365-02-3 |
| EINECS | 624-637-4 |
| InChI | InChI=1/C10H17NO3/c1-10(2,3)14-9(13)11-6-4-5-8(11)7-12/h7-8H,4-6H2,1-3H3 |
N-(tert-butoxycarbonyl)-D-prolinal - Physico-chemical Properties
| Molecular Formula | C10H17NO3 |
| Molar Mass | 199.25 |
| Density | 1.059g/mLat 25°C(lit.) |
| Boling Point | 228°C(lit.) |
| Specific Rotation(α) | +83°(23℃, neat) |
| Flash Point | >230°F |
| Vapor Presure | 0.005mmHg at 25°C |
| Appearance | Liquid |
| Specific Gravity | 1.059 |
| Color | Colorless to yellow |
| pKa | -3.03±0.40(Predicted) |
| Storage Condition | -20°C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.461(lit.) |
| MDL | MFCD01321389 |
N-(tert-butoxycarbonyl)-D-prolinal - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29339980 |
N-(tert-butoxycarbonyl)-D-prolinal - Introduction
N-(tert-butoxycarbonyl)-D-prolinal(N-(tert-butoxycarbonyl)-D-prolinal) is an organic compound with the following properties:
1. appearance: white solid powder.
2. molecular formula: C12H19NO4.
3. Molecular weight: 241.28g/mol.
4. Melting point: about 82-86°C.
5. Solubility: Soluble in organic solvents such as alcohol and ester.
6. stability: stable under conventional experimental conditions.
N-(tert-butoxycarbonyl)-D-prolinal main uses are as follows:
1. Organic synthesis: As an intermediate in chemical synthesis, it can be used to synthesize D-proline analogs and related compounds.
2. Drug research: N-(tert-butoxycarbonyl)-D-prolinal can be used to synthesize and study peptide or protein inhibitors, agonists, etc.
N-(tert-butoxycarbonyl)-D-prolinal is prepared as follows:
The synthesis of N-(tert-butoxycarbonyl)-D-prolinal is generally completed by a two-step reaction. First, D-prolinal is reacted with tert-butyl dimethyl silicone (t-BuMe2SiH) to form the N-(tert-butoxycarbonyl)-D-prolinal derivative, and then the protecting group (Boc) is removed by acid treatment to obtain the N-(tert-butoxycarbonyl)-D-prolinal.
Regarding the safety information of N-(tert-butoxycarbonyl)-D-prolinal, you need to pay attention to the following matters:
1. Since N-(tert-butoxycarbonyl)-D-prolinal has not been widely used, its toxicity and safety data are limited. Please follow relevant laboratory procedures and take necessary personal protective measures when using it.
2. Avoid inhaling powder or solution, avoid contact with skin and eyes, and avoid ingestion in the mouth. In case of accidental contact, rinse immediately with plenty of water and seek medical advice.
3. Please operate in a well-ventilated laboratory and avoid contact with flammable substances.
4. in storage and use, should follow the relevant regulations and safe operation of chemicals.
1. appearance: white solid powder.
2. molecular formula: C12H19NO4.
3. Molecular weight: 241.28g/mol.
4. Melting point: about 82-86°C.
5. Solubility: Soluble in organic solvents such as alcohol and ester.
6. stability: stable under conventional experimental conditions.
N-(tert-butoxycarbonyl)-D-prolinal main uses are as follows:
1. Organic synthesis: As an intermediate in chemical synthesis, it can be used to synthesize D-proline analogs and related compounds.
2. Drug research: N-(tert-butoxycarbonyl)-D-prolinal can be used to synthesize and study peptide or protein inhibitors, agonists, etc.
N-(tert-butoxycarbonyl)-D-prolinal is prepared as follows:
The synthesis of N-(tert-butoxycarbonyl)-D-prolinal is generally completed by a two-step reaction. First, D-prolinal is reacted with tert-butyl dimethyl silicone (t-BuMe2SiH) to form the N-(tert-butoxycarbonyl)-D-prolinal derivative, and then the protecting group (Boc) is removed by acid treatment to obtain the N-(tert-butoxycarbonyl)-D-prolinal.
Regarding the safety information of N-(tert-butoxycarbonyl)-D-prolinal, you need to pay attention to the following matters:
1. Since N-(tert-butoxycarbonyl)-D-prolinal has not been widely used, its toxicity and safety data are limited. Please follow relevant laboratory procedures and take necessary personal protective measures when using it.
2. Avoid inhaling powder or solution, avoid contact with skin and eyes, and avoid ingestion in the mouth. In case of accidental contact, rinse immediately with plenty of water and seek medical advice.
3. Please operate in a well-ventilated laboratory and avoid contact with flammable substances.
4. in storage and use, should follow the relevant regulations and safe operation of chemicals.
Last Update：2024-04-09 21:21:28
Supplier List
Spot supply
Product Name: N-(tert-Butoxycarbonyl)-D-prolinal Visit Supplier Webpage Request for quotationCAS: 73365-02-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: N-Boc-D-Prolinal Visit Supplier Webpage Request for quotationCAS: 73365-02-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: N-Boc-D-Prolinal Visit Supplier Webpage Request for quotation
CAS: 73365-02-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 73365-02-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: N-(tert-Butoxycarbonyl)-D-prolinal Visit Supplier Webpage Request for quotationCAS: 73365-02-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: N-Boc-D-Prolinal Visit Supplier Webpage Request for quotationCAS: 73365-02-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: N-Boc-D-Prolinal Visit Supplier Webpage Request for quotation
CAS: 73365-02-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 73365-02-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History