N-(tert-butoxycarbonyl)-O-tert-butylserine
3-tert-butoxy-2-(tert-butoxycarbonylamino)propanoic acid
CAS: 13734-38-8
Molecular Formula: C12H23NO5
N-(tert-butoxycarbonyl)-O-tert-butylserine - Names and Identifiers
| Name | 3-tert-butoxy-2-(tert-butoxycarbonylamino)propanoic acid |
| Synonyms | BOC-SER-OTBU BOC-SER(BU)-OH BOC-SER(BUT)-OH BOC-SER(TBU)-OH Boc-Ser(But)-OH Boc-Ser(tBu)-OH Boc-Hser(Bzl)-Oh BOC-L-SER(TBU)-OH BOC-SERINE(TBU)-OH BOC-O-T-BUTYL-L-SERINE BOC-O-TERT-BUTYL-L-SERINE N-Boc-O-tert-butyl-L-serine N-(tert-butoxycarbonyl)-O-tert-butylserine N-(tert-butoxycarbonyl)-O-tert-butyl-L-serine 3-tert-butoxy-2-(tert-butoxycarbonylamino)propanoic acid |
| CAS | 13734-38-8 |
| EINECS | 604-015-9 |
| InChI | InChI=1/C12H23NO5/c1-11(2,3)17-7-8(9(14)15)13-10(16)18-12(4,5)6/h8H,7H2,1-6H3,(H,13,16)(H,14,15)/t8-/m0/s1 |
N-(tert-butoxycarbonyl)-O-tert-butylserine - Physico-chemical Properties
| Molecular Formula | C12H23NO5 |
| Molar Mass | 261.31 |
| Density | 1.087±0.06 g/cm3(Predicted) |
| Melting Point | 80℃ |
| Boling Point | 383.1±37.0 °C(Predicted) |
| Flash Point | 185.5°C |
| Vapor Presure | 6.22E-07mmHg at 25°C |
| pKa | 3.55±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.463 |
N-(tert-butoxycarbonyl)-O-tert-butylserine - Introduction
N-tert-Butoxycarbonyl-O-tert-butyl-L-serine is a compound commonly abbreviated as Boc-L-serine. The following is an introduction to its nature, use, preparation and safety information:
Nature:
Boc-L-serine is a white crystalline powder with a special amino acid structure. It is soluble in some organic solvents (such as dimethyl sulfoxide) at room temperature, but has low solubility in water.
Use:
Boc-L-serine is a commonly used protected amino acid in organic synthesis. By adding a Boc protecting group to the hydroxyl group of serine, unintended reactions in chemical reactions can be prevented. Boc-L-serine are widely used as intermediates in the synthesis of peptides, proteins and pharmaceutical research.
Preparation Method:
The preparation of Boc-L-serine usually involves the following steps: First, the hydroxyl group of L-serine is reacted with tert-butoxycarbonyl chloride to obtain N-tert-butoxycarbonyl-L-serine ester; then, the ester is reacted with tert-butyl ammonia to produce the target product Boc-L-serine.
Safety Information:
The Boc-L-serine is generally safe under normal use conditions, but it still needs to be handled with caution. It may cause irritation to the skin, eyes and respiratory tract, so direct contact should be avoided. Wear protective gloves, goggles and masks during operation. In addition, it should be stored in a dry, cool place, away from fire and oxidizing agents.
Please note that the above information is for reference only. Specific operation instructions and safety information should refer to relevant chemical literature and laboratory safety operation manual.
Nature:
Boc-L-serine is a white crystalline powder with a special amino acid structure. It is soluble in some organic solvents (such as dimethyl sulfoxide) at room temperature, but has low solubility in water.
Use:
Boc-L-serine is a commonly used protected amino acid in organic synthesis. By adding a Boc protecting group to the hydroxyl group of serine, unintended reactions in chemical reactions can be prevented. Boc-L-serine are widely used as intermediates in the synthesis of peptides, proteins and pharmaceutical research.
Preparation Method:
The preparation of Boc-L-serine usually involves the following steps: First, the hydroxyl group of L-serine is reacted with tert-butoxycarbonyl chloride to obtain N-tert-butoxycarbonyl-L-serine ester; then, the ester is reacted with tert-butyl ammonia to produce the target product Boc-L-serine.
Safety Information:
The Boc-L-serine is generally safe under normal use conditions, but it still needs to be handled with caution. It may cause irritation to the skin, eyes and respiratory tract, so direct contact should be avoided. Wear protective gloves, goggles and masks during operation. In addition, it should be stored in a dry, cool place, away from fire and oxidizing agents.
Please note that the above information is for reference only. Specific operation instructions and safety information should refer to relevant chemical literature and laboratory safety operation manual.
Last Update：2024-04-09 21:01:54
Supplier List
Spot supply
Product Name: Boc-O-tert-butyl-L-serine Visit Supplier Webpage Request for quotationCAS: 13734-38-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Boc-O-tert-butyl-L-serine Visit Supplier Webpage Request for quotationCAS: 13734-38-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History