N-3-Azetidinyl-methanesulfonamide - Names and Identifiers
N-3-Azetidinyl-methanesulfonamide - Physico-chemical Properties
Molecular Formula | C4H10N2O2S
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Molar Mass | 150.2 |
Storage Condition | 2-8°C(protect from light) |
N-3-Azetidinyl-methanesulfonamide - Introduction
N-(3-Azetidinyl) methanesulfonamide, chemical formula C11H16N2O3S, is an organic compound.
Properties: N-(3-Azetidinyl) methanesulfonamide is a white solid with deliquescent properties, soluble in water and organic solvents such as methanol, ethanol and dichloromethane. It has a certain alkaline, can react with acid to form salts. In addition, it is also an electrophile that can undergo substitution reactions with nucleophiles in chemical reactions.
Purpose: N-(3-azetidinyl) methanesulfonamide has a wide range of applications in organic synthesis. It is often used as an isocyanate activation reagent, can make the ester and alcohol amination reaction, the corresponding amine compounds. At the same time, it is also used in the preparation of drugs, dyes and intermediates in chemical processes.
Preparation method: The preparation method of N-(3-azetidinyl) methanesulfonamide is relatively simple. One common method is the Baiger reaction, where 3-azetidinamine is reacted with methanesulfonyl chloride and the resulting product is then neutralized with a base and finally purified by crystallization to give the desired product.
Safety information: N-(3-azetidinyl) methanesulfonamide is safe, but should avoid prolonged contact with skin and eyes, avoid inhaling its dust. Pay attention to personal protective measures during use, such as wearing gloves, goggles and protective clothing. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. At the same time, avoid contact with oxidants and strong acids during storage to avoid danger.
Last Update:2024-04-09 21:11:58