N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-3,3-DIPHENYLALANINE - Names and Identifiers
Name | FMOC-D-3,3-DIPHENYLALANINE
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Synonyms | FMOC-D-DPH-OH RARECHEM BK PT 0198 FMOC-D-(3-PHENYL)PHE-OH FMOC-D-3,3-DIPHENYLALANINE Fmoc-3,3-Diphenyl-D-alanine N-FMOC-BETA-PHENYL-D-PHENYLALANINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-3,3-DIPHENYLALANINE N-(9-FLUORENYLMETHOXYCARBONYL)-BETA-PHENYL-D-PHENYLALANINE N-[(9H-fluoren-9-ylmethoxy)carbonyl]-beta-phenyl-L-phenylalanine N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-BETA-PHENYL-D-PHENYLALANINE 2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3,3-diphenylpropanoic acid
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CAS | 189937-46-0
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InChI | InChI=1/C30H25NO4/c32-29(33)28(27(20-11-3-1-4-12-20)21-13-5-2-6-14-21)31-30(34)35-19-26-24-17-9-7-15-22(24)23-16-8-10-18-25(23)26/h1-18,26-28H,19H2,(H,31,34)(H,32,33)/t28-/m1/s1 |
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-3,3-DIPHENYLALANINE - Physico-chemical Properties
Molecular Formula | C30H25NO4
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Molar Mass | 463.52 |
Density | 1.262±0.06 g/cm3(Predicted) |
Melting Point | 116.5-119.5°C(lit.) |
Boling Point | 676.5±55.0 °C(Predicted) |
Flash Point | 362.9°C |
Vapor Presure | 3.18E-19mmHg at 25°C |
pKa | 3.57±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.642 |
Physical and Chemical Properties | Storage Conditions: Store at 0 ℃ WGK Germany:3 |
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-3,3-DIPHENYLALANINE - Risk and Safety
Hazard Symbols | Xi - Irritant
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WGK Germany | 3 |
Hazard Class | IRRITANT |
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-3,3-DIPHENYLALANINE - Introduction
FMOC-D-3,3-DIPHENYLALANINE is an organic compound with the following properties:
1. Appearance: FMOC-D-3,3-DIPHENYLALANINE is a white powder.
2. Solubility: It dissolves in organic solvents such as dimethyl sulfoxide (DMSO), dichloromethane (DCM) and methanol, but has low solubility in water.
FMOC-D-3, the main use of 3-DIPHENYLALANINE is an amino acid protective agent in organic synthesis. It is widely used in the field of peptide synthesis and protein chemical synthesis. It can increase the selectivity of the reaction by protecting the amino group of the amino acid, and can easily remove the protecting group when necessary.
The method for preparing FMOC-D-3,3-DIPHENYLALANINE is usually to react D-3,3-DIPHENYLALANINE with Fmoc photosensitive protecting group. The reaction is usually carried out in an organic solvent, such as DMF (dimethylformamide) or dichloromethane, and at low temperatures.
Regarding the safety information of FMOC-D-3,3-DIPHENYLALANINE, the following points should be noted:
1. It should avoid inhalation, intake and skin contact. When in use, wear appropriate personal protective equipment such as lab gloves, goggles and ventilation outside the laboratory.
2. FMOC-D-3,3-DIPHENYLALANINE is potentially irritating, so contact with eyes, skin and mucous membranes should be avoided.
3. Please keep it properly and keep away from fire and oxidant when using.
In the use and handling of FMOC-D-3,3-DIPHENYLALANINE, the safe handling of the relevant chemicals should be followed, and the compound should be properly managed.
Last Update:2024-04-09 20:49:11