N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-BENZYL-L-SERINE - Names and Identifiers
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-BENZYL-L-SERINE - Physico-chemical Properties
Molecular Formula | C25H23NO5
|
Molar Mass | 417.45 |
Density | 1.279±0.06 g/cm3(Predicted) |
Boling Point | 642.4±55.0 °C(Predicted) |
Flash Point | 342.3°C |
Vapor Presure | 2.22E-17mmHg at 25°C |
Appearance | Powder |
Color | Pale brown |
pKa | 3.41±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.621 |
MDL | MFCD00065674 |
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-BENZYL-L-SERINE - Risk and Safety
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
FLUKA BRAND F CODES | 10 |
HS Code | 29242990 |
Hazard Class | IRRITANT |
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-BENZYL-L-SERINE - Introduction
fmoc-O-benzyl-L-serine(fmoc-O-benzyl-L-serine) is an organic compound having a specific structure. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
fmoc-O-benzyl-L-serine is a white to yellow crystalline powder with low solubility. It is a non-natural amino acid derivative and has an Fmoc protecting group for amino acid protection. The compounds are well soluble in organic solvents such as dimethyl sulfoxide (DMSO) or methylene chloride.
Use:
fmoc-O-benzyl-L-serine are commonly used reagents in organic synthesis, especially in solid phase synthesis and peptide synthesis. It can be used as an amino acid unit for the construction of peptide chains, which can be introduced into polypeptide molecules by deprotection reactions.
Preparation Method:
fmoc-O-benzyl-L-serine can be prepared by organic synthesis methods. A common synthetic method is to react O-benzyl-L-serine with Fmoc-OSu(N-hydroxysuccinimide) to form fmoc-O-benzyl-L-serine. This synthesis generally requires that it be carried out under an inert atmosphere.
Safety Information:
fmoc-O-benzyl-L-serine is a chemical reagent that should be used in accordance with general laboratory safety procedures. It may cause irritation to the skin, eyes and respiratory tract, so care should be taken to avoid direct contact during operation. The operation should be carried out in a well-ventilated laboratory and appropriate personal protective equipment, such as laboratory gloves and protective glasses, should be worn.
In addition, if the compound is to be used, ensure that it is legally purchased, stored and disposed of in accordance with applicable regulatory requirements. In any chemical experiment, if you encounter any problems or unexpected situations, please immediately seek the help of professional chemists.
Last Update:2024-04-09 20:52:54