N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-CHLORO-D-PHENYLALANINE
Fmoc-2-chloro-D-phenylalanine
CAS: 205526-22-3
Molecular Formula: C24H20ClNO4
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-CHLORO-D-PHENYLALANINE - Names and Identifiers
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-CHLORO-D-PHENYLALANINE - Physico-chemical Properties
| Molecular Formula | C24H20ClNO4 |
| Molar Mass | 421.87 |
| Density | 1.337±0.06 g/cm3(Predicted) |
| Melting Point | 154°C |
| Boling Point | 640.9±55.0 °C(Predicted) |
| Specific Rotation(α) | 46 º (c=1,EtOAc) |
| pKa | 3.72±0.11(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Physical and Chemical Properties | alpha:46 o (c=1,EtOAc) |
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-CHLORO-D-PHENYLALANINE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-CHLORO-D-PHENYLALANINE - Introduction
Fmoc-2-chloro-D-phenylalanine is an amino acid derivative with specific chemical properties and application value. The following is a description of its nature, use, preparation and safety information:
Nature:
1. The molecular formula of Fmoc-2-chloro-D-phenylalanine is C24H19ClNO4, and the relative molecular mass is 415.86.
2. It is a white or off-white crystalline powder, soluble in a variety of organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane and methanol.
3. Fmoc-2-chloro-D-phenylalanine is a very important amino acid protecting group, often used in solid phase synthesis.
Use:
1. Fmoc-2-chloro-D-phenylalanine is the key raw material in solid phase synthesis, which can be used in peptide synthesis, peptide synthesis, drug synthesis and other fields.
2. It has good acid-base stability, can be synthesized under acidic or environmental conditions, and can help the directional synthesis of complex polypeptides.
Method:
The preparation method of Fmoc-2-chloro-D-phenylalanine is more complicated, and it is generally synthesized step by step by organic synthesis reaction. The specific synthesis process is complex and requires the use of multi-step reactions and synthesis strategies, including esterification, substitution, deprotection and other steps.
Safety Information:
1. Fmoc-2-chloro-D-phenylalanine should pay attention to prevent inhalation and contact caused by dust during operation.
2. Avoid contact with skin, eyes and mucous membranes, wear appropriate protective equipment when using, such as gloves, safety glasses.
3. During storage and transportation, keep a dry and well-ventilated environment to avoid high temperature and fire.
4. Fmoc-2-chloro-D-phenylalanine dust is irritating. If it comes into contact with skin or eyes, rinse with plenty of water immediately and seek medical assistance.
Please note that the above information is for reference only. If you need specific operation guidance or more detailed safety information, please consult professional institutions or experts in related fields.
Nature:
1. The molecular formula of Fmoc-2-chloro-D-phenylalanine is C24H19ClNO4, and the relative molecular mass is 415.86.
2. It is a white or off-white crystalline powder, soluble in a variety of organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane and methanol.
3. Fmoc-2-chloro-D-phenylalanine is a very important amino acid protecting group, often used in solid phase synthesis.
Use:
1. Fmoc-2-chloro-D-phenylalanine is the key raw material in solid phase synthesis, which can be used in peptide synthesis, peptide synthesis, drug synthesis and other fields.
2. It has good acid-base stability, can be synthesized under acidic or environmental conditions, and can help the directional synthesis of complex polypeptides.
Method:
The preparation method of Fmoc-2-chloro-D-phenylalanine is more complicated, and it is generally synthesized step by step by organic synthesis reaction. The specific synthesis process is complex and requires the use of multi-step reactions and synthesis strategies, including esterification, substitution, deprotection and other steps.
Safety Information:
1. Fmoc-2-chloro-D-phenylalanine should pay attention to prevent inhalation and contact caused by dust during operation.
2. Avoid contact with skin, eyes and mucous membranes, wear appropriate protective equipment when using, such as gloves, safety glasses.
3. During storage and transportation, keep a dry and well-ventilated environment to avoid high temperature and fire.
4. Fmoc-2-chloro-D-phenylalanine dust is irritating. If it comes into contact with skin or eyes, rinse with plenty of water immediately and seek medical assistance.
Please note that the above information is for reference only. If you need specific operation guidance or more detailed safety information, please consult professional institutions or experts in related fields.
Last Update：2024-04-09 15:17:55
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