N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-BETA-CYCLOPROPYL-L-ALANINE
Fmoc-.beta.-cyclopropyl-Ala-OH
CAS: 214750-76-2
Molecular Formula: C21H21NO4
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-BETA-CYCLOPROPYL-L-ALANINE - Names and Identifiers
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-BETA-CYCLOPROPYL-L-ALANINE - Physico-chemical Properties
| Molecular Formula | C21H21NO4 |
| Molar Mass | 351.4 |
| Density | 1.291±0.06 g/cm3(Predicted) |
| Melting Point | 157-159°C |
| Boling Point | 583.5±33.0 °C(Predicted) |
| Solubility | DMF (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White |
| pKa | 3.89±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-BETA-CYCLOPROPYL-L-ALANINE - Risk and Safety
| HS Code | 29225090 |
| Hazard Class | IRRITANT |
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-BETA-CYCLOPROPYL-L-ALANINE - Introduction
Fmoc-.beta.-cyclopropyl-Ala-OH is a derivative of an amino acid protecting group that is commonly used in peptide synthesis in solid phase synthesis. The following is a description of the nature, use, formulation and safety information of the Fmoc-.beta.-cyclopropyl-Ala-OH:
Nature:
Fmoc-.beta.-cyclopropyl-Ala-OH is a white crystalline powder with the chemical formula C24H25NO4 with a relative molecular mass of 415.5. It is insoluble in water at normal temperature, but soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and methylene chloride. The compound is stable under light but sensitive to acids, bases and oxidants.
Use:
Fmoc-.beta.-cyclopropyl-Ala-OH are mainly used in the solid phase synthesis of peptides and are used as protecting groups in the growth of peptide chains. It can be reacted with other amino acid residues and activating agents (such as dioxylcarbonyl chloride, DCC) by solid phase synthesis to form polypeptide chains with specific sequences.
Method: The preparation of
Fmoc-.beta.-cyclopropyl-Ala-OH generally involves the N-protecting group formation of L-cyclopropylalanine. The Fmoc group is first reacted with L-cyclopropylalanine to form the Fmoc-.beta.-cyclopropyl-Ala-OH. The preparation process requires the use of organic solvents, and attention should be paid to the control of reaction conditions and the treatment of waste liquid.
Safety Information:
Fmoc-.beta.-cyclopropyl-Ala-OH are generally relatively safe under normal conditions of use. However, as a chemical agent, it may cause irritation to the skin, eyes and respiratory system. During the operation, appropriate laboratory safety measures should be taken, such as wearing chemical safety glasses, gloves and protective clothing. If inadvertently touched or inhaled into the body, immediately rinse the affected area with water and seek medical help.
Nature:
Fmoc-.beta.-cyclopropyl-Ala-OH is a white crystalline powder with the chemical formula C24H25NO4 with a relative molecular mass of 415.5. It is insoluble in water at normal temperature, but soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and methylene chloride. The compound is stable under light but sensitive to acids, bases and oxidants.
Use:
Fmoc-.beta.-cyclopropyl-Ala-OH are mainly used in the solid phase synthesis of peptides and are used as protecting groups in the growth of peptide chains. It can be reacted with other amino acid residues and activating agents (such as dioxylcarbonyl chloride, DCC) by solid phase synthesis to form polypeptide chains with specific sequences.
Method: The preparation of
Fmoc-.beta.-cyclopropyl-Ala-OH generally involves the N-protecting group formation of L-cyclopropylalanine. The Fmoc group is first reacted with L-cyclopropylalanine to form the Fmoc-.beta.-cyclopropyl-Ala-OH. The preparation process requires the use of organic solvents, and attention should be paid to the control of reaction conditions and the treatment of waste liquid.
Safety Information:
Fmoc-.beta.-cyclopropyl-Ala-OH are generally relatively safe under normal conditions of use. However, as a chemical agent, it may cause irritation to the skin, eyes and respiratory system. During the operation, appropriate laboratory safety measures should be taken, such as wearing chemical safety glasses, gloves and protective clothing. If inadvertently touched or inhaled into the body, immediately rinse the affected area with water and seek medical help.
Last Update：2024-04-10 22:29:15
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CAS: 214750-76-2
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QQ: 3008007409
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CAS: 214750-76-2
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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