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N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-D-PHENYLALANINE

N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-D-PHENYLALANINE

CAS: 114526-00-0

Molecular Formula: C18H19NO4

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N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-D-PHENYLALANINE - Names and Identifiers

Name N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-D-PHENYLALANINE
Synonyms Z-D-MEPHE-OH
CBZ-N-METHYL-D-PHENYLALANINE
N-Methyl-N-Cbz-D-phenylalanine
N-CBZ-N-METHYL-D-PHENYLALANINE
N-Benzyloxycarbonyl-N-methyl-D-phenylalanine
N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-D-PHENYLALANINE
(R)-2-(((Benzyloxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid
(2R)-2-[methyl(phenylmethoxycarbonyl)amino]-3-phenylpropanoic acid
CAS 114526-00-0

N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-D-PHENYLALANINE - Physico-chemical Properties

Molecular FormulaC18H19NO4
Molar Mass313.35

N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-D-PHENYLALANINE - Introduction

N-Methyl-N-Cbz-D-alanine is an organic compound with the chemical formula C20H23NO5, which contains an N-methyl-N-Cbz-D-alanine group in its structure.

Nature:
N-Methyl-N-Cbz-D-alanine is a solid substance having a white or almost white appearance. It is soluble in organic solvents such as chloroform and dimethylformamide at normal temperature and hardly soluble in water. It has a certain degree of stability, but avoid prolonged exposure to air and strong light to prevent decomposition and loss of activity.

Use:
N-methyl-N-Cbz-D-alanine is often used as a protecting group in organic synthesis. The N-methyl-N-Cbz-D-alanine generated by the reaction can protect the amine functional group to prevent unwanted reaction or destruction during the reaction. It can be used as an intermediate in the preparation of polypeptide compounds and pharmaceuticals.

Method:
The preparation of N-methyl-N-Cbz-D-alanine can be carried out by a variety of methods. The common method is to react D-alanine with N-benzyl-N-methyl-N-nitroformate to obtain N-benzyl-N-methyl-N-nitro-D-alanine ester, and then reduce the nitro group to amine group through a series of reduction and migration reactions, deprotection under appropriate acidic conditions yields the final N-methyl-N-Cbz-D-alanine.

Safety Information:
N-methyl-N-Cbz-D-alanine is relatively safe under normal operating conditions, but as a chemical, protection measures are still required. Direct contact with skin and eyes should be avoided, and suitable protective gloves and glasses should be worn during operation. At the same time, it should be operated in a well-ventilated laboratory environment to avoid inhaling its dust or solution. In case of accidental contact or inhalation, please seek medical attention.
Last Update:2024-04-09 21:11:58
N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-D-PHENYLALANINE
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Shanghai Macklin Biochemical Co., Ltd
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Product Name: N-((Benzyloxy)carbonyl)-N-methyl-d-phenylalanine Visit Supplier Webpage Request for quotation
CAS: 114526-00-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
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Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: N-((Benzyloxy)carbonyl)-N-methyl-d-phenylalanine Visit Supplier Webpage Request for quotation
CAS: 114526-00-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
View History
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