N-ALPHA-FMOC-O-2-BROMO-CBZ-L-TYROSINE
Fmoc-Tyr(2-Br-Z)-OH
CAS: 147688-40-2
Molecular Formula: C32H26BrNO7
N-ALPHA-FMOC-O-2-BROMO-CBZ-L-TYROSINE - Names and Identifiers
N-ALPHA-FMOC-O-2-BROMO-CBZ-L-TYROSINE - Physico-chemical Properties
| Molecular Formula | C32H26BrNO7 |
| Molar Mass | 616.46 |
| Density | 1.452±0.06 g/cm3(Predicted) |
| Boling Point | 791.4±60.0 °C(Predicted) |
| pKa | 2.89±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Physical and Chemical Properties | Storage Conditions: 2-8 ℃ |
N-ALPHA-FMOC-O-2-BROMO-CBZ-L-TYROSINE - Introduction
Fmoc-Tyr (2-br-Z)-OH is an organic compound with the following properties:
1. Appearance: usually white or white solid powder.
2. Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.
3. Melting point: about 170-175 degrees Celsius.
Fmoc-Tyr(2-Br-Z)-OH is often used in solid phase synthesis as a protecting group in peptide synthesis. It can protect the amino group of tyrosine in the process of peptide synthesis, so as to avoid unnecessary reaction and improve the selectivity of synthetic peptide chain. When it is necessary to remove the protecting group, it can be removed by acid treatment.
The method for preparing Fmoc-Tyr(2-Br-Z)-OH is as follows:
First, L-tyrosine is reacted with bromobenzylchloroformate under sodium carbonate and alkaline conditions to produce N-bromobenzylchloroformate tyrosine salt. Then, it is reacted with Fmoc-OSu(Fmoc-O-sulfonyl lactate) in diethyl carbonate hydrochloride buffer to obtain the target product.
Regarding safety information, Fmoc-Tyr(2-Br-Z)-OH is a chemical reagent with certain potential hazards. During use, the following safety precautions should be paid attention:
1. Avoid contact with skin and eyes.
2. Use should wear appropriate protective gloves and goggles.
3. Maintain a well-ventilated laboratory environment during operation.
4. Follow the correct operating procedures and avoid inhalation and swallowing.
5. In case of accidental contact or inhalation, rinse with water immediately and seek medical attention if necessary.
It should be noted that the above safety information is for reference only. The product manual should be carefully read and the laboratory safety operation specifications should be followed.
1. Appearance: usually white or white solid powder.
2. Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.
3. Melting point: about 170-175 degrees Celsius.
Fmoc-Tyr(2-Br-Z)-OH is often used in solid phase synthesis as a protecting group in peptide synthesis. It can protect the amino group of tyrosine in the process of peptide synthesis, so as to avoid unnecessary reaction and improve the selectivity of synthetic peptide chain. When it is necessary to remove the protecting group, it can be removed by acid treatment.
The method for preparing Fmoc-Tyr(2-Br-Z)-OH is as follows:
First, L-tyrosine is reacted with bromobenzylchloroformate under sodium carbonate and alkaline conditions to produce N-bromobenzylchloroformate tyrosine salt. Then, it is reacted with Fmoc-OSu(Fmoc-O-sulfonyl lactate) in diethyl carbonate hydrochloride buffer to obtain the target product.
Regarding safety information, Fmoc-Tyr(2-Br-Z)-OH is a chemical reagent with certain potential hazards. During use, the following safety precautions should be paid attention:
1. Avoid contact with skin and eyes.
2. Use should wear appropriate protective gloves and goggles.
3. Maintain a well-ventilated laboratory environment during operation.
4. Follow the correct operating procedures and avoid inhalation and swallowing.
5. In case of accidental contact or inhalation, rinse with water immediately and seek medical attention if necessary.
It should be noted that the above safety information is for reference only. The product manual should be carefully read and the laboratory safety operation specifications should be followed.
Last Update：2024-04-09 21:01:54
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Product Name: FMOC-TYR(2-BR-Z)-OH Visit Supplier Webpage Request for quotation
CAS: 147688-40-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 147688-40-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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