N-ALPHA-T-BOC-L-ARG
N(alpha)-boc-L-arginine
CAS: 13726-76-6
Molecular Formula: C11H22N4O4
N-ALPHA-T-BOC-L-ARG - Names and Identifiers
| Name | N(alpha)-boc-L-arginine |
| Synonyms | BOC-ARG-OH Boc-Arg-OH BOC-ARGININE BOC-L-ARGININE Boc-L-arginine N-T-BOC-L-ARGININE N-ALPHA-T-BOC-L-ARG N(alpha)-boc-L-arginine N-TERT-BUTOXYCARBONYL-L-ARGININE N-ALPHA-T-BUTOXYCARBONYL-L-ARGININE NALPHA-(TERT-BUTOXYCARBONYL)-L-ARGININE N-alpha-(tert-butoxycarbonyl)-L-arginine N~2~-(tert-butoxycarbonyl)-N~5~-(diaminomethylidene)-L-ornithine |
| CAS | 13726-76-6 |
| EINECS | 237-295-2 |
| InChI | InChI=1/C11H22N4O4/c1-11(2,3)19-10(18)15-7(8(16)17)5-4-6-14-9(12)13/h7H,4-6H2,1-3H3,(H,15,18)(H,16,17)(H4,12,13,14)/t7-/m0/s1 |
N-ALPHA-T-BOC-L-ARG - Physico-chemical Properties
| Molecular Formula | C11H22N4O4 |
| Molar Mass | 274.32 |
| Density | 1.28±0.1 g/cm3(Predicted) |
| Melting Point | 117-119°C |
| Flash Point | >230°F |
| BRN | 2419628 |
| pKa | 3.92±0.21(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.54 |
N-ALPHA-T-BOC-L-ARG - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29252900 |
N-ALPHA-T-BOC-L-ARG - Introduction
Boc-arginine is an organic compound that is one of the protecting groups of arginine. Boc represents a t-butoxycarbonyl protecting group (tert-butoxycarbonyl), which acts to protect the amino group by reacting with the amino group in arginine to form an amide structure.
Boc-arginine has important applications in biochemistry, medicinal chemistry and organic synthesis. It can be used as an activator for the synthesis of polypeptides, proteins and drug molecules. In polypeptide synthesis, Boc-arginine is commonly used as a standard amino acid protecting group in the art. It can provide selective protection of the amino group to avoid accidental reactions during the synthesis.
The preparation of Boc-arginine generally involves two steps. First, t-butyl chloroformate (tert-butyl chloroformate) is reacted with arginine under basic conditions to produce a t-butoxycarbonyl protected ester of Boc-arginine. The Boc-arginine is then reduced to free arginine by hydrolysis of the protected ester structure.
When using Boc-arginine, it is necessary to pay attention to its safety information. It may cause irritation to the skin, eyes and respiratory tract, so it is necessary to take appropriate protective measures when handling, such as wearing gloves, goggles and protective masks. In addition, Boc-Arginine can be a hazard to the environment, so safe practices need to be followed during handling and disposal.
Boc-arginine has important applications in biochemistry, medicinal chemistry and organic synthesis. It can be used as an activator for the synthesis of polypeptides, proteins and drug molecules. In polypeptide synthesis, Boc-arginine is commonly used as a standard amino acid protecting group in the art. It can provide selective protection of the amino group to avoid accidental reactions during the synthesis.
The preparation of Boc-arginine generally involves two steps. First, t-butyl chloroformate (tert-butyl chloroformate) is reacted with arginine under basic conditions to produce a t-butoxycarbonyl protected ester of Boc-arginine. The Boc-arginine is then reduced to free arginine by hydrolysis of the protected ester structure.
When using Boc-arginine, it is necessary to pay attention to its safety information. It may cause irritation to the skin, eyes and respiratory tract, so it is necessary to take appropriate protective measures when handling, such as wearing gloves, goggles and protective masks. In addition, Boc-Arginine can be a hazard to the environment, so safe practices need to be followed during handling and disposal.
Last Update：2024-04-09 21:01:54
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Product Name: Boc-Arg-OH Visit Supplier Webpage Request for quotationCAS: 13726-76-6
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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