N-ALPHA-T-BUTOXYCARBONYL-D-HYDROXYPROLINE - Names and Identifiers
Name | (2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
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Synonyms | BOC-D-HYP-OH Boc-D-trans-Hyp-OH N-Boc-trans-D-Hyp-OH BOC-D-PRO(4-HYDROXY)-OH BOC-TRANS-4-HYDROXY-D-PROLINE N-BOC-CIS-7-HYDROXY-D-PROLINE N-Boc-trans-4-Hydroxy-D-proline (2R,4S)-N-Boc-4-hydroxy-D-proline N-T-BOC-TRANS-4-HYDROXY-D-PROLINE (2R,4S)-N-Boc-cis-4-hydroxy-D-proline (2R,4S)-N-Boc-trans-4-hydroxy-D-proline N-ALPHA-T-BUTOXYCARBONYL-D-HYDROXYPROLINE (4S)-1-(tert-butoxycarbonyl)-4-hydroxy-D-proline 1-tert-Butoxycarbonyl-(2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid (2R,4S)-4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester (2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
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CAS | 147266-92-0
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EINECS | 803-000-6 |
InChI | InChI=1/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7+/m0/s1 |
N-ALPHA-T-BUTOXYCARBONYL-D-HYDROXYPROLINE - Physico-chemical Properties
Molecular Formula | C10H17NO5
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Molar Mass | 231.25 |
Density | 1.312±0.06 g/cm3(Predicted) |
Melting Point | 123°C |
Boling Point | 390.9±42.0 °C(Predicted) |
Flash Point | 190.193°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 3.80±0.40(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.531 |
MDL | MFCD01861341 |
N-ALPHA-T-BUTOXYCARBONYL-D-HYDROXYPROLINE - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36 - Irritating to the eyes
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Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
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WGK Germany | 3 |
Hazard Class | IRRITANT |
N-ALPHA-T-BUTOXYCARBONYL-D-HYDROXYPROLINE - Introduction
(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID is an organic compound with the following characteristics:
Nature:
1. Appearance: white crystalline solid
2. Molecular formula: C11H17NO5
3. Molecular weight: 247.26g/mol
4. Solubility: Soluble in organic solvents, such as dichloromethane, ethanol and methanol
5. Stability: stable at room temperature, but sensitive to light and heat
Use:
(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID is often used as an intermediate in organic synthesis and an important reagent in the research field. It can be used in the synthesis of drugs, bioactive compounds and peptide compounds.
Method:
Preparation of (2R,4S)-Methods for N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID are generally achieved by chemical synthesis. One common method is by reacting trans-4-hydroxy-d-proline with an N-protecting group, such as a Boc Group, to obtain the desired product.
Safety Information:
Use the following safety information:
1. The compound may be irritating, please avoid direct contact with skin, eyes and respiratory tract.
2. In the process of operation, should follow the laboratory safety procedures, wear appropriate protective measures, including laboratory gloves and goggles.
3. Storage should be placed in a dry, cool place, avoid contact with oxygen, moisture and strong acid and other substances.
Last Update:2024-04-09 02:00:42